| Customization: | Available |
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| CAS No.: | 9026-12-4 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Ribonuclease T1, derived from the fungus Aspergillus oryzae, is an endoribonuclease enzyme that specifically cleaves single-stranded RNA at the 3' end of guanosine residues. This enzyme is highly selective for guanosine, resulting in the cleavage of RNA at guanosine positions and leading to the generation of guanosine 3'-phosphate and 5'-hydroxyl RNA fragments.
Ribonuclease T1 has been widely utilized in biochemical and molecular biology research for its ability to cleave RNA at specific sites, enabling the precise mapping of RNA secondary and tertiary structures. It has been particularly valuable in RNA structure determination studies, as well as in the characterization of RNA-protein interactions.
Moreover, the enzyme has also found applications in biotechnology, such as in the generation of RNA oligonucleotides with defined 3' termini, which are utilized in various experimental and therapeutic contexts.
In summary, Ribonuclease T1 from Aspergillus oryzae is a valuable tool in RNA research and biotechnology, owing to its specific endoribonuclease activity targeting guanosine residues in single-stranded RNA. Its applications encompass RNA structure analysis, RNA-protein interaction studies, and the generation of defined RNA oligonucleotides.
Application
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | RIBONUCLEASE T1 |
| Synonyms: | guanyl-specificrnase;ribonucleasec2;ribonucleasech;ribonucleasef1;ribonucleasen1;ribonucleasen3;ribonucleaseppi;Ribonulease T1 froM Aspergillus oryzae |
| CAS: | 9026-12-4 |
| MF: | |
| MW: | 0 |
| EINECS: | 232-809-1 |
| Product Categories: | |
| Mol File: | Mol File |
| storage temp. | 2-8°C |
| form | ammonium sulfate suspension |
| WGK Germany | 3 |
| RTECS | RF0753000 |
| F | 10 |
| Uses | Ribonuclease T1 (RNase T1) from Aspergillus oryzae is used to digest denatured RNA prior to sequencing and is used for protein folding studies . |
| Biochem/physiol Actions | Ribonuclease T1 (RNase T1) from Aspergillus oryzae is an endoribonuclease that hydrolyzes after G residues. Cleavage occurs between the 3′-phosphate group of a guanidine ribonucleotide and 5′-hydroxyl of the adjacent nucleotide. The initial product is a 2′:3′ cyclic phosphate nucleoside that is hydrolyzed to the corresponding 3′-nucleoside phosphate. It differs from Pancreatic RNase in that it attacks the guanine sites specifically to yield 3′-GMP and oligonucleotides with a 3′-GMP terminal group. |
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