| Customization: | Available |
|---|---|
| CAS No.: | 606-68-8 |
| Formula: | C21h30n7nao14p2 |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Dihydronicotinamide adenine dinucleotide disodium salt, commonly abbreviated as NADH, is the reduced form of nicotinamide adenine dinucleotide (NAD+), a coenzyme present in all living cells. NADH plays a pivotal role in cellular metabolism, particularly serving as a carrier of electrons and hydrogen ions in redox reactions.
Within the cell, NADH participates in essential metabolic pathways such as glycolysis, the citric acid cycle, and oxidative phosphorylation. In these processes, it acts as a crucial electron donor, aiding in the production of adenosine triphosphate (ATP) and providing energy for various cellular functions.
Additionally, NADH serves as a coenzyme for numerous enzymatic reactions, facilitating the catalysis of diverse biochemical processes including the breakdown of nutrients and the synthesis of macromolecules.
Research has also focused on the potential therapeutic applications of NADH, particularly in the context of mitochondrial function, energy metabolism, and neurological disorders. Studies have explored its role in enhancing cellular energy production, protecting against oxidative stress, and potentially ameliorating the effects of certain neurological conditions.
In summary, NADH is an essential coenzyme involved in cellular energy production, redox reactions, and enzymatic processes. Its significance in cellular metabolism and its potential implications for therapeutic interventions highlight its importance in understanding fundamental biological processes and exploring potential treatment strategies.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | NADH, disodium salt |
| Synonyms: | eta-d-ribofuranosyl-3-pyridinecarboxamide,disodiumsalt;BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE, REDUCED FORM DISODIUM SALT;BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE, REDUCED, 2NA;BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT;BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE, DISODIUM SALT;beta-Nicotinamide adenine dinucleotidedisodium salthydrate;eta-d-ribofuranosyl-3-pyridinecarboxamide, disodium salt beta-nicotinamide adenine dinucleotide, disodium salt, hydrate beta-nicotinamide adenine dinucleotide disodium salt,trihydrate;NICOTINAMIDE ADENINE DINUCLEOTIDE (REDUCED) DISODIUM SALT extrapure |
| CAS: | 606-68-8 |
| MF: | C21H30N7NaO14P2 |
| MW: | 689.44 |
| EINECS: | 210-123-3 |
| Product Categories: | Bases & Related Reagents;Carbohydrates & Derivatives;Cofactors and SubstratesBiochemicals and Reagents;Nucleotides;Phosphorylating and Phosphitylating Agents;nucleoside;NAD and AnalogsResearch Essentials;Nucleosides and NucleotidesEnzymes, Inhibitors, and Substrates;Oxidation-ReductionMetabolic Pathways;Core Bioreagents;Electron Transport and Cellular Respiration;Metabolic Pathways;Metabolites and Cofactors on the Metabolic Pathways Chart;TCA;Bioproducts;Cofactor;Oxidation-Reduction;Cofactors;Enzymes, Inhibitors, and Substrates;Biochemicals and Reagents;NAD and Analogs;Nucleosides, Nucleotides, Oligonucleotides;606-68-8 |
| Mol File: | 606-68-8.mol |
| Melting point | 140-142°C |
| density | 1.955 at 20ºC |
| vapor pressure | 0.73Pa at 20-50ºC |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: 50 mg/mL, clear to nearly clear, yellow |
| form | Powder |
| color | Yellow |
| PH | 7.5 (100mg/mL in water, ±0.5) |
| Water Solubility | soluble |
| BRN | 5230241 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | QRGNQKGQENGQSE-WUEGHLCSSA-L |
| LogP | -1.96 at 21ºC and pH7 |
| Surface tension | 69.22mN/m at 1.022g/L and 20ºC |
| CAS DataBase Reference | 606-68-8 |
| EPA Substance Registry System | Reduced .beta.-nicotinamide adenine dinucleotide disodium salt (606-68-8) |
| Hazard Codes | Xn |
| Risk Statements | 23/24/25-36/37/38-39/23/24/25-40-22 |
| Safety Statements | 26-36/37/39-45-24/25-36/37 |
| WGK Germany | 3 |
| F | 3-10-23 |
| TSCA | Yes |
| HS Code | 29349990 |
| Description | β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). |
| Chemical Properties | White to beige powder |
| Uses | One of the biologically active forms of nicotinic acid. Serves as a coenzyme of hydrogenases and dehydrogenases. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Occurs in 2 forms, α-NAD and β-NAD, distinguished by the configuration of the ribosyl nicotinamide linkage. Only the β-anomer is bioactive. |
| Uses | β-Nicotinamide adenine dinucleotide, reduced disodium salt has been used in the preparation of standard curve. |
| Definition | NADH, disodium salt is a dehydrogenase complex that is the reduced formof NAD. As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations. |
| Biological Functions | NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle. |
| General Description | β-Nicotinamide adenine dinucleotide (β-NAD) regulates energy metabolism and immunity. It is a cofactor for mitochondrial deacetylase sirtuin-3 enzyme and modulates inflammasome assembly. β-NAD supresses interleukin-1β levels in monocytic cells in inflammatory syndromes. β-NAD released by neurosecretory cells is a potential neurotransmitter. β-NAD is a vascular mediator in lung endothelial cells and may play a protective role against cytokine mediated inflammation. |
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