| Customization: | Available |
|---|---|
| CAS No.: | 4090-29-3 |
| Formula: | C21h27n7o13p2s |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Thionicotinamide adenine dinucleotide (thio-NAD) is a derivative of nicotinamide adenine dinucleotide (NAD) that contains a sulfur atom in place of the oxygen atom in the nicotinamide ribose. Similar to NAD, thio-NAD plays a crucial role in cellular redox processes and energy metabolism.
Thio-NAD is involved in redox reactions as a coenzyme, participating in electron transfer processes in various biochemical pathways. It serves as a co-substrate for enzymes that catalyze redox reactions, facilitating the transfer of electrons and contributing to the generation of ATP, the primary source of energy in cells. Additionally, thio-NAD is integral to metabolic pathways such as glycolysis, the citric acid cycle, and oxidative phosphorylation, where it functions in the transfer of energy-rich electrons.
In research settings, thio-NAD is utilized as a tool to study redox processes, enzymatic mechanisms, and metabolic pathways. Its use as a coenzyme analog allows for the investigation of the roles of NAD-dependent enzymes and redox regulation in biological systems.
Moreover, thio-NAD has been studied for its potential therapeutic applications, particularly in the context of metabolic disorders and age-related conditions. Research has explored its role in modulating cellular redox balance, mitochondrial function, and metabolic pathways, with implications for conditions such as diabetes, neurodegenerative diseases, and aging-related metabolic dysregulation.
In summary, thio-NAD is a sulfur-containing derivative of NAD with pivotal roles in cellular redox processes, energy metabolism, and enzymatic reactions. Its significance in research and its potential implications for therapeutic interventions underscore its importance in understanding cellular function and metabolic regulation.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | Thionicotinamide adenine dinucleotide |
| Synonyms: | THIONICOTINAMIDE ADENINE DINUCLEOTIDE;THIONICOTINAMIDE-DPN;THIO-NAD;adenosine 5'-(trihydrogen diphosphate), 5'->5'-ester with 3-(aminothioxomethyl)-1-beta-D-ribofuranosylpyridinium--ate;Thionicotinamide-NAD;beta-Thionicotinamide adenine dinucleotide, oxidised form 92+%;3-Thiocarbamoylpyridine adenine dinucleotide;3-Thionicotinamide adenine dinucleotide |
| CAS: | 4090-29-3 |
| MF: | C21H27N7O13P2S |
| MW: | 679.49 |
| EINECS: | 223-828-6 |
| Product Categories: | nucleoside |
| Mol File: | 4090-29-3.mol |
| storage temp. | -20°C |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| InChIKey | DQRRIGAXTAXHLR-NNYOXOHSSA-N |
| CAS DataBase Reference | 4090-29-3 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | - |
| HS Code | 29349990 |
| Description | Thionicotinamide adenine dinucleotide is an analog of NAD. Use of Thio-NAD instead of NAD as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in absorbance at 405 nM, the most commonly available wavelength on microplate readers. |
| Chemical Properties | Light yellow powder |
| Uses | Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity. |
| Application | Thionicotinamide adenine dinucleotide (thio-NAD) is a NAD derivative used in the determination of Carnitine by an enzymic cycling method with carnitine dehydrogenase. |
| Biochem/physiol Actions | Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells. |
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