| CAS No.: | 5625-37-6 |
|---|---|
| Formula: | C8h18n2o6s2 |
| EINECS: | 227-057-6 |
| Appearance: | Powder |
| Type: | Pharmaceutical Intermediates |
| Quality: | Refined |
| Samples: |
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| Customization: |
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| PIPES Chemical Properties |
| Melting point | >300 °C (lit.) |
| density | 1.4983 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.1 M NaOH: 0.25 g/mL, clear, colorless |
| form | Micro-Crystalline Powder |
| color | White |
| PH Range | 6.1 - 7.5 |
| pka | 6.8(at 25ºC) |
| Water Solubility | Soluble in water. |
| λmax | λ: 260 nm Amax: 0.055 λ: 280 nm Amax: 0.040 |
| Merck | 14,7479 |
| BRN | 817713 |
| InChIKey | XWGRYGKFRRLUQQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 5625-37-6(CAS DataBase Reference) |
| EPA Substance Registry System | 1,4-Piperazinediethanesulfonic acid (5625-37-6) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-37/39-26 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29335995 |
| MSDS Information |
| PIPES Usage And Synthesis |
| Uses | Piperazine-N, N'-bis- (2-ethanesulphonic acid) ultra -pure >99.5%) is an important chemical intermedia in all kinds of chemical fields. 1,4-Piperazinediethanesulfonic acid, piperazine-N, N'-bis- (2-ethanesulfonic acid) (PIPES) is also one of the zwitterion buffers and the most appropriate buffer for the biological experiments using an intracellular solution since the Pk2 of Pipes is 6.8 at 20 degrees Celsius. |
| Chemical Properties | White/clear crystalline powder |
| Uses | A buffering agent with a pKa near physiological pH. |
| Purification Methods | Purify PIPES from boiling water (maximum solubility is about 1g/L) or as described for ADA [N-(2-acetamido)iminodiacetic acid above]. [Good et al. Biochemistry 5 469 1966, Beilstein 23/12 V 380.] |
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