Alizarin-3-Methyliminodiacetic Acid CAS No 3952-78-1 Biological Stain

• Customization: Available
• CAS No.: 3952-78-1
• Formula: C19h15no8
• Model NO.: YB004
• EINECS: 223-544-2
• Appearance: Powder
• Type: Pharmaceutical Intermediates
• Quality: Refined
• Colour: Brown
• Samples: Available
• Purity: 99%
• Certificates: ISO9001/SGS
• Package: 1kg/5kg/10kg/25kg
• Stocks: in Stock
• Lead Time: 5-7 Working Days
• Shelf Life: 2-3 Years
• Site Audit: Available
• Transport: Air/Express/Sea
• MOQ: 10g
• Transport Package: Drum/Bottle/Bags
• Specification: Dye content, 70%
• Trademark: Yunbang
• Origin: China

Product Description

Alizarin-3-methyliminodiacetic acid CAS NO 3952-78-1 Biological stain

 

Company Informations:
Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.

General description

It is a dye employed to stain mineralized bones of the preserved specimen from vertebrates.

Application

Alizarin-3-methyliminodiacetic acid has been used:

• for live staining of mineralized bone matrix.
• to double-label the bone for dynamic bone histomorphometry at the femoral mid-diaphysis in the rat.
• as a label in histomorphometry of the tibial diaphysis to indicate new bone formation in the rat.

Product Name:	ALIZARIN COMPLEXONE
CAS:	3952-78-1
MF:	C19H15NO8
MW:	385.32
EINECS:	223-544-2
Product Categories:	Photometric Reagents (Complexone);Analytical Chemistry;Anthraquinones;Chelating Reagents;Complexones;Hydroxyanthraquinones
Mol File:	3952-78-1.mol

ALIZARIN COMPLEXONE Chemical Properties

Melting point	~185 °C (dec.)
Boiling point	511.79°C (rough estimate)
density	1.4951 (rough estimate)
refractive index	1.5000 (estimate)
storage temp.	2-8°C
solubility	DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.125 mg/ml
pka	1.71±0.10(Predicted)
form	Fine Powder
color	Brown
Water Solubility	Slightly soluble (0.2 g/L)
BRN	2190028
Stability:	Incompatible with strong oxidizing agents.
InChI	InChI=1S/C19H15NO8/c21-13(22)7-20(8-14(23)24)6-9-5-12-15(19(28)16(9)25)18(27)11-4-2-1-3-10(11)17(12)26/h1-5,25,28H,6-8H2,(H,21,22)(H,23,24)
InChIKey	PWIGYBONXWGOQE-UHFFFAOYSA-N
SMILES	C(O)(=O)CN(CC(O)=O)CC1=C(O)C(O)=C2C(=C1)C(=O)C1=C(C=CC=C1)C2=O
CAS DataBase Reference	3952-78-1(CAS DataBase Reference)
EPA Substance Registry System	Glycine, N-(carboxymethyl)-N-[(9,10-dihydro-3,4-dihydroxy-9,10-dioxo-2-anthracenyl)methyl]- (3952-78-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
RTECS	AH0585000
TSCA	Yes
HS Code	29225090

 

ALIZARIN COMPLEXONE Usage And Synthesis

Chemical Properties	Brown-orange crystals, insoluble in water
Uses	Alizarin-3-methyliminodiacetic acid has been used: for live staining of mineralized bone matrix to double-label the bone for dynamic bone histomorphometry at the femoral mid-diaphysis in the rat as a label in histomorphometry of the tibial diaphysis to indicate new bone formation in the rat
Uses	Alizarin is the main ingredient for the manufacture of the madder lake pigments known to painters as Rose madder and Alizarin crimson. A notable use of alizarin in modern times is as a staining agent in biological research because it stains free calcium and certain calcium compounds a red or light purple color. Alizarin Red is used in a biochemical assay to determine, quantitatively by colorimetry, the presence of calcific deposition by cells of an osteogenic lineage.
Definition	ChEBI: A dihydroxyanthraquinone compound in which the hydroxy groups are at C-1 and C-2 and which has a bis[(carboxymethyl)amino]methyl substituent at the 3-position.
Hazard	Anthraquinones are toxic by ingestion: vomiting, diarrhea, kidney and liver damage, and coma; Deaths have been reported after children ingested Rhamnus berries; Has antiretroviral activity; An irritant; Harmful by ingestion, inhalation, or skin absorption; Toxic if swallowed.
Purification Methods	It is purified by suspending it in 0.1M NaOH (1g in 50mL), filtering the solution and extracting alizarin with 5 successive portions of CH2Cl2. Then add HCl dropwise to precipitate the reagent, stirring the solution in an ice bath. Filter the precipitate onto a glass filter, wash it with cold water and dry it in a vacuum desiccator over KOH [Ingman Talanta 20 135 1973, Beilstein 14 IV 931].

 

 

 

 

 

 

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