| Customization: | Available |
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| CAS No.: | 9027-67-2 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Terminal transferase, also known as terminal deoxynucleotidyl transferase (TdT), is a template-independent DNA polymerase enzyme that is involved in the addition of nucleotides to the 3' hydroxyl (OH) terminus of DNA molecules. Unlike other DNA polymerases, TdT does not require a template strand for its activity and can add nucleotides to the growing DNA chain in a non-templated manner.
TdT plays a crucial role in the process of V(D)J recombination, which is a key mechanism in the generation of antibody diversity in vertebrates. During V(D)J recombination, TdT contributes to the diversity of immunoglobulin and T cell receptor genes by adding random nucleotides to the junctions of gene segments, leading to the generation of a wide range of antigen receptor specificities.
Furthermore, TdT has been identified in various stages of lymphoid cell development, particularly in immature lymphocytes, where it participates in the generation of diverse antigen receptor repertoires. Its activity contributes to the adaptive immune response by enabling the recognition of a broad array of antigens.
In addition to its role in immune diversity, TdT has implications in DNA repair processes and has been associated with certain types of leukemia and lymphoma.
In summary, terminal transferase (TdT) is a specialized DNA polymerase that plays a critical role in the diversity of antigen receptor genes in vertebrates, contributing to the adaptive immune response and immune system function. Its unique template-independent activity is essential for the generation of diverse antibody and T cell receptor specificities.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE |
| Synonyms: | EC 2.7.7.31;TDT;TDTASE;TDT ENZYME;TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE (TDT);TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE;TERMINAL TRANSFERASE;NUCLEOSIDE TRIPHOSPHATE:DNA DEOXYNUCLEOTIDYL-EXOTRANSFERASE |
| CAS: | 9027-67-2 |
| MF: | C4H10S3 |
| MW: | 0 |
| EINECS: | 232-819-6 |
| Product Categories: | enzyme |
| Mol File: | Mol File |
| storage temp. | −20°C |
| form | buffered aqueous glycerol solution |
| EPA Substance Registry System | Nucleotidyltransferase, terminal deoxyribo- (9027-67-2) |
| Hazard Codes | T |
| Risk Statements | 49-52/53 |
| Safety Statements | 22-24/25-61-45-53 |
| RIDADR | UN 3316 9 |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 3504009000 |
| Uses | The enzyme solution contains terminal deoxynucleotidyl transferase from calf thymus, recombinant in E. coli, needed to perform the TUNEL reaction for detecting apoptosis in situ. The TUNEL reaction mixture is used to label DNA strand breaks for detecting and quantitating apoptotic cell death at the single-cell level in cells and tissues. |
| General Description | TUNEL enzyme solution, containing terminal deoxynucleotidyl transferase from calf thymus recombinant in E. coli. One of the two components required for performing the TUNEL reaction to detect apoptosis in situ. |
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