| Customization: | Available |
|---|---|
| CAS No.: | 9001-45-0 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Beta-glucuronidase is an enzyme that catalyzes the hydrolysis of β-D-glucuronic acid residues from the end of mucopolysaccharides, such as heparan sulfate and chondroitin sulfates. This enzyme plays a crucial role in the metabolism and catabolism of various substances in the body.
In biological and medical research, beta-glucuronidase is often utilized in enzymatic assays to cleave glucuronide conjugates of various compounds, thus allowing the measurement of the aglycones (the original compounds) that were conjugated. This process is particularly important in drug metabolism studies and toxicology research, where the measurement of the aglycones provides insights into the kinetics and pathways of drug metabolism and excretion.
Furthermore, beta-glucuronidase is used in molecular biology techniques to remove glucuronic acid residues from glycosaminoglycans during the preparation of DNA samples for analysis. Additionally, it is employed in diagnostic assays to detect the presence of glucuronides as a marker of certain diseases and conditions.
General description
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | β-Glucuronidase |
| Synonyms: | beta-d-glucuronidase;beta-glucuronidas;beta-glucuronideglucuronohydrolase;β-d-glucuronide glucuronosohydrolase;β-glucuronidase from bovine liver;β-glucuronidase from escherichia coli;β-glucuronidase from helix pomatia;β-glucuronidase from patella vulgata (keyhole limpet) |
| CAS: | 9001-45-0 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 232-606-8 |
| Product Categories: | enzyme;3.2.x.x Glycosidases;3.x.x.x Hydrolases;Application Index;Carbohydrate and PTM AnalysisApplication Index;Carbohydrate hydrolysis&PTM analysis;Diagnostic and Analytical EnzymesAnalytical Enzymes;Molluskan SourceEnzyme Class Index;β-Glucuronidase;Carbohydrate HydrolysisEnzymes, Inhibitors, and Substrates |
| Mol File: | Mol File |
| storage temp. | -20°C |
| form | powder |
| color | yellow-brown |
| Merck | 13,4480 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37-45-23 |
| WGK Germany | 3 |
| RTECS | LZ8990000 |
| F | 3-10 |
| Uses | β-glucuronidase is used as a reporter gene in GUS assays to monitor gene expression. |
| Uses | β-Glucuronidase was used in the study of Cer-β-glucuronide synthesis and evaluation of β-glucuronidase(s) from Escherichia coli or intestinal segments to release the head group. |
| Uses | In the determination of urinary steroids and of steroid conjugates in blood. |
| General Description | β-Glucuronidase from Escherichia coli is similar to human glucuronidase enzyme and corresponds to molecular weight close to 69-71 kDa and has an pH optimum of 6.5-7.5. It belongs to family-2 glycosyl hydrolase and has active site residues glutamic acid 394, tyrosine 468 and glutamic acid 504. |
| Biochem/physiol Actions | β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain. |
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