CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)

Product Details
Customization: Available
CAS No.: 26305-03-3
Formula: C34h63n5o9
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  • CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
  • CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
  • CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
  • CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
  • CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
  • CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
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  • Overview
  • Company Informations
  • Product Description
  • FAQ
  • Our Advantages
  • Product analysis
  • Detailed Photos
Overview

Basic Info.

Model NO.
YB157
EINECS
247-600-0
Environmental Protection
No
Certification
ISO9001
Color
Colorless Needles
Classification
Coenzyme
Function
Catalysis
Appearance
Powder
Type
Pharmaceutical Intermediates
Quality
Refined
Colour
Colorless Needles
Samples
Available
Certificates
ISO9001/SGS
Package
1kg/5kg/10kg/25kg
Stocks
in Stock
Lead Time
5-7 Working Days
Shelf Life
2-3 Years
Site Audit
Available
Transport
Air/Express/Sea
MOQ
1 Unit
Payment Method
LC/Tt/DAP/OA
Form
Powder
Purity
99%
Transport Package
Drum/Bottle/Bags
Specification
90%
Trademark
Yunbang OEM
Origin
China

Product Description

CAS 26305-03-3 Pepstatin A powder microbial 90% (HPLC)
 
Company Informations

Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.

The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.


Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.

 
Product Description

Pepstatin A is a potent and specific inhibitor of acid proteases, particularly targeting the enzyme pepsin. It is a naturally occurring peptide derived from actinomycetes, exhibiting strong binding affinity for the active site of acid proteases. Pepstatin A's inhibitory activity against pepsin, a gastric protease, makes it a valuable tool in biochemical and biomedical research.

This inhibitor is widely used in the laboratory setting to inhibit acid proteases in cell and tissue extracts, as well as in purification procedures for acid proteases. Its application extends to the study of intracellular protein degradation and the regulation of acid protease activity, contributing to the understanding of cellular processes and diseases influenced by protease function.

In addition to its research applications, Pepstatin A is also utilized in pharmaceutical and biotechnological industries for the development of therapeutic agents targeting acid proteases. Its ability to selectively inhibit pepsin-like enzymes has potential implications in the treatment of conditions associated with abnormal protease activity, such as certain gastrointestinal disorders.

In summary, Pepstatin A is a natural peptide inhibitor with specificity towards acid proteases, particularly pepsin. Its utility spans from laboratory research to potential therapeutic development, offering valuable insights into protease function and serving as a basis for the exploration of medical interventions targeting acid proteases.

General description

Pepstatin A is a naturally occurring chemotactic peptide and inhibitor of aspartic proteases that was initially isolated from culture filtrates of various Actinomycetes species, with the initial name simply of "pepstatin". This name was later modified to "pepstatin A" to distinguish the original pepstatin from later derivatives. Pepstatin A notably contains the unusual amino acid 4-amino-hydroxy-6-methylheptanoic acid (AHMHA), which is known also as statine. The amino acid sequence of pepstatin A is N-Isovaleryl-L-Valyl-L-Valyl-AHMHA-L-Alanyl-AHMHA.

Application

Can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes. For this application, the working concentration is typically between 1-10 μM.
 
FAQ

1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?
A: We can have a discussion.

3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.

4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.

5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Our Advantages

1. 90days quality guarantee for exchange.

2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.

3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.

 

Product analysis
 
 
 
Product Name: Pepstatin
Synonyms: ahpatininc;pepsininhibitors735a;procidins735a;PEPSTATIN;X-VAL-VAL-STATYL-ALA-STATIN;AHMHA ISOVALERYL-L-VAL-L-VAL-AHMHA-L-ALA-STA;Pepstatin A, Ultra Pure;pepstatin|Pep A|PEP|peptistatin A|pepstatine A|Pepstatin A|pepstatine
CAS: 26305-03-3
MF: C34H63N5O9
MW: 685.89
EINECS: 247-600-0
Product Categories: Antibiotics;Inhibitor;peptides;Pepetides;ProteaseInhibitors
Mol File: 26305-03-3.mol
 
Melting point  233 °C (dec.)(lit.)
Boiling point  695.91°C (rough estimate)
density  1.1340 (rough estimate)
refractive index  1.7500 (estimate)
storage temp.  2-8°C
pka 4.17±0.10(Predicted)
form  White solid
color  Colorless needles
optical activity Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).
BRN  2201362
Stability: Stable. Incompatible with strong bases, strong acids.
InChIKey JKGWASGTXVCDML-LXTPJMTPSA-N
CAS DataBase Reference 26305-03-3(CAS DataBase Reference)
Safety Statements  22-24/25
WGK Germany  2
RTECS  SC6155000
10
HS Code  29241990
Toxicity LD50 in mice, rats, rabbits, dogs (mg/kg): 1090, 875, 820, 450 i.p.; all >2000 orally (Umezawa, 1970)
 
Detailed Photos

 

CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)
CAS 26305-03-3 Pepstatin a Powder Microbial 90% (HPLC)



 

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