| Customization: | Available |
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| CAS No.: | 9025-24-5 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Carboxypeptidase B is an enzyme that belongs to the family of exopeptidases, which catalyze the hydrolysis of peptide bonds at the carboxy-terminal end of proteins and peptides. Specifically, carboxypeptidase B cleaves off individual amino acids from the C-terminus of peptides and proteins, resulting in the release of a free amino acid. This enzymatic activity is crucial for the digestion of proteins and the processing of peptide hormones.
Carboxypeptidase B is highly specific for cleaving basic amino acids, such as lysine or arginine, from the C-terminus of peptides. Its substrate specificity contributes to its role in the final stages of protein digestion, where it acts on peptides produced by the action of other proteolytic enzymes, such as trypsin and chymotrypsin. Additionally, carboxypeptidase B is involved in the processing and inactivation of peptide hormones and neuropeptides by removing specific basic amino acids from their C-termini.
This enzyme is found in various tissues and organs, including the pancreas, where it contributes to the processing of proenzymes into their active forms, and the intestinal mucosa, where it aids in the final breakdown of peptides into absorbable amino acids.
The activity of carboxypeptidase B is essential for the proper digestion and assimilation of dietary proteins, as well as for the regulation of peptide hormone signaling. Its enzymatic function contributes to the maintenance of nutrient supply and the modulation of physiological processes in the body.
In summary, carboxypeptidase B is an exopeptidase enzyme that plays a vital role in the hydrolysis of peptide bonds at the C-terminus of proteins and peptides, contributing to protein digestion, peptide hormone processing, and the regulation of physiological functions. Its activity is fundamental for the breakdown of dietary proteins and the modulation of peptide signaling in various biological processes.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | CARBOXYPEPTIDASE B |
| Synonyms: | PROTEIN CARBOXYPEPTIDASE B;PROTAMINASE;PEPTIDYL-L-LYSINE[L-ARGININE] HYDROLASE;CARBOXYPEPTIDASE B, PORCINE PANCREAS;EC 3.4.17.2;IUB: 3.4.17.2;carboxypeptidase B from hog pancreas;RecoMbinant Carboxypeptidase B |
| CAS: | 9025-24-5 |
| MF: | C31H38N4O7S |
| MW: | 610.72102 |
| EINECS: | 232-788-9 |
| Product Categories: | |
| Mol File: | 9025-24-5.mol |
| storage temp. | -20°C |
| form | powder |
| color | white |
| Hazard Codes | Xi,B,Xn |
| Risk Statements | 36-42-36/37/38 |
| Safety Statements | 26-36-36/37-24-22 |
| WGK Germany | 3 |
| Uses | Carboxypeptidase B from Sigma has been used as a reference for assaying carboxypeptidase activity in lysed pituitary granules derived from the anterior and intermediate lobes of rat. The enzyme has also been used to digest plasma samples by removing C-terminal basic amino acids, to get a distinct band for each allotype during C4 electrophoresis. |
| Uses | The enzyme from Sigma has been used to develop homogeneous time-resolved fluorescence (HTRF) assay for measuring carboxypeptidase B activity in a miniaturized high-throughput screening format. It has been used to evaluate the impact of the C-terminal lysine(s) in human plasminogen binding to Bifidobacterium. The effect of treatment with carboxypeptidase B, which is a C-terminal lysine-specific endopeptidase, is measured using flow cytometry analysis. |
| General Description | Native carboxypeptidase B catalyzes the release of C-terminal from basic amino acids, arginine, lysine, or ornithine from polypeptides. Inhibited by EDTA and other Zn2+ chelators. |
| Biochem/physiol Actions | Carboxypeptidase B is a proteolytic enzyme capable of rapidly hydrolyzing peptide bonds to release certain carboxyl-terminal basic amino acids from peptides and proteins. Its molecular mass is 34,300±600 Da. It contains one non-dialyzable gram atom of zinc per mole. The enzyme activity is inhibited by metal chelating agents 1, 10-phenanthroline, 8-hydroxyquinoline-5-sulfonic acid, and 2,2′-dipyridyl. |
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