CAS 9064-47-5 Type II-a, Lyophilized Powder Histone

• Customization: Available
• CAS No.: 9064-47-5
• Formula: /
• Model NO.: YB284
• EINECS: 297-235-6
• Environmental Protection: No
• Certification: ISO9001
• Color: White
• Classification: Biological Reagent
• Function: in The Field of Genetics, It Is Used as a Standard
• Appearance: Powder
• Type: Pharmaceutical Intermediates
• Quality: Refined
• Colour: White
• Samples: Available
• Purity: 99%
• Certificates: ISO9001/SGS
• Package: 1kg/5kg/10kg/25kg
• Stocks: in Stock
• Lead Time: 5-7 Working Days
• Shelf Life: 2-3 Years
• Site Audit: Available
• Transport: Air/Express/Sea
• MOQ: 10g
• Transport Package: Drum/Bottle/Bags
• Specification: 99%
• Trademark: Yunbang
• Origin: China

Product Description

CAS 9064-47-5 Type II-A, lyophilized powder Histone
 

Company Informations

Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.

The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.
 

Product Description

General description

Histones are octameric proteins containing H3, H4, H2A and H2B. It is the core protein around which DNA is wound forming the nucleosome structure. The core histone proteins contain globular domains. Each protein is composed of basic amino acids at its N-terminal. The H2A has an extra amino acid at its C-terminal end forming a histone tail. The nucleosome structure is stabilized by the linker histones during chromatin condensation.

Application

Histone from calf thymus has been used:

• in methyltransferase reaction mixture for methyltransferase assay
• in in vitro binding assay, to explore the potential binding of the MORF4 (mortality factor on chromosome 4) - related gene on chromosome 15 (MRG15) chromo domain with histone
• in in vitro coculture assays, to stimulate liver resident Kupffer cells

FAQ

1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?
A: We can have a discussion.

3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.

4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.

5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Product analysis

Product Name:	HISTONE TYPE VIII-S
Synonyms:	histone type iii-S from calf thymus;histone type iii-ss from calf thymus;histone type viii-S from calf thymus;Histones nucleo froM calf thyMus;Histones,dried(Calf thyMus);Histone III (calfthyMus) (9CI);f3histonefraction;histoneiii(calfthymus)
CAS:	9064-47-5
MF:	NULL
MW:	0
EINECS:	297-235-6
Product Categories:	Protein Kinase C (PKC)Peptides for Cell Biology;Protein Kinase Related Peptides;Biochemicals and Reagents;Protein Kinase Substrates;Serine/Threonine Kinase Biology;Serine/Threonine Kinase Substrates;Bovine;Proteins and Derivatives
Mol File:	Mol File

storage temp.	2-8°C
solubility	H2O: soluble10mg/mL, clear to hazy, colorless to light yellow
form	lyophilized powder
BRN	1895465

WGK Germany	3
RTECS	MS3450700
F	10-21
Toxicity	LD50 intravenous in rat: 45mg/kg

 

Uses	Histone is suitable for use: as a positive control in the in vitro kinase assay to examine the ability of Cdc2-cyclin B1 to phosphorylate GST-CD-4 protein in Cdk5 activity assay in histone H1 kinase assay as a Poly(ADP-ribose) (PAR) acceptor in the assessment of in vitro PAR polymerase activity as an acceptor of ^32P from [γ-^32P]ATP in order to measure protein kinase activity of lysate from small and large luteal cells
General Description	Histones are octameric proteins containing H3, H4, H2A and H2B. It is the core protein around which DNA is wound forming the nucleosome structure. The core histone proteins contain globular domains. Each protein is composed of basic amino acids at its N-terminal. The H2A has an extra amino acid at its C-terminal end forming a histone tail. The nucleosome structure is stabilized by the linker histones during chromatin condensation.
Biochem/physiol Actions	Histones are a group of proteins characterized by high levels of lysine and arginine that form reversible complexes with DNA. Based on the fractions, the molar mass of histones varies between 11-21kDa. Five different fractions have been isolated and characterized. They include H1 (lysine rich), H2a and H2b that are slightly lysine rich, H3 and H4 that are arginine rich. H1 acts as a link between "beads" (nu bodies) on the chromatin chain.

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