| Customization: | Available |
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| CAS No.: | 9054-89-1 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Superoxide radicals are generated as natural byproducts of aerobic metabolism and are known to be highly reactive and potentially damaging to cellular components, including proteins, lipids, and DNA. SOD provides a primary defense against these harmful effects by converting superoxide radicals into less reactive species, thereby preventing the accumulation of oxidative damage.
There are several isoforms of SOD found in different cellular compartments, including cytoplasmic, mitochondrial, and extracellular forms. Each isoform plays a distinct role in neutralizing superoxide radicals in specific cellular locations, contributing to overall oxidative stress defense and redox balance.
The activity of SOD is critical for maintaining cellular homeostasis and is implicated in various physiological and pathological processes, including aging, neurodegenerative diseases, inflammation, and cancer. As a result, SOD has been a subject of extensive research and holds potential therapeutic significance in addressing conditions associated with oxidative stress.
In summary, superoxide dismutase serves as a key antioxidant enzyme, safeguarding cells against the damaging effects of superoxide radicals and contributing to the overall maintenance of cellular redox balance and health.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | Superoxide dismutase |
| Synonyms: | Dismutase,superoxide;superoxide dismutase from bovine*erythrocytes;superoxide dismutase microbial sources*from esche;Superoxide Dismutase, Human, Recomb., E. coli;EC 1.15.1.1;CU/ZN SOD;CU/ZN-SUPEROXIDE DISMUTASE;IUB: 1.15.1.1 |
| CAS: | 9054-89-1 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 232-943-0 |
| Product Categories: | Enzymes;proteins |
| Mol File: | Mol File |
| storage temp. | -20°C |
| solubility | Dissolves readily at 5 mg/mL in 0.05 M potassium phosphate buffer, pH 7.8, containing 0.1 mM EDTA. |
| form | powder |
| color | blue-gray |
| Hazard Codes | B |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-22-23 |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 35079090 |
| Description | Superoxide dismutase is widely present in the human body, including the skin and its appendages. |
| Uses | Superoxide dismutase is used as an excellent therapeutic agent to combat reactive oxygen species-mediated diseases such as cancer, inflammatory diseases, cystic fibrosis, ischemia, aging, rheumatoid arthritis, neurodegenerative diseases, and diabetes. However, the enzyme has some limitations in clinical applications. Therefore, SOD conjugates and mimetics have been developed to improve its therapeutic efficiency. |
| Brand name | Palosein Veterinary (Oxis). |
| benefits | Based on the metal cofactors present in the active sites, Superoxide dismutases (SODs) can be classified into four distinct groups: Copper-Zinc-SOD (Cu, Zn-SOD), Iron SOD (Fe-SOD), Manganese SOD (Mn-SOD), and Nickel SOD. The enzyme can serve as an anti-inflammatory agent and can also prevent precancerous cell changes. SOD is used in cosmetics and personal care products as an anti-aging ingredient and antioxidant due to its ability to reduce free radical damage to the skin, therefore preventing wrinkles, fine lines, and age spots, and it also helps with wound healing, softens scar tissue, protects against UV rays, and reduces other signs of aging. It has been reported that SOD has an important link in several human health problems including RBC-related disorders, cystic fibrosis (CF), postcholecystectomy pain syndrome, malignant breast disease, steroid-sensitive nephrotic syndrome, amyotrophic lateral sclerosis, neuronal apoptosis, AIDS, and cancer. In many animal models having myocardial ischemia-reperfusion injury, inflammation, cerebral ischemia-reperfusion injury, etc., SOD enzymes are found to be very effective. Furthermore, a strong association between the activity of SOD and Alzheimer's disease has been suggested by some researchers[1-2]. |
| Clinical Use | Superoxide dismutase is widely studied and used for anti-inflammatory, anti-tumor, radiation protection and anti-aging applications. |
| Purification Methods | The dismutase is purified by DEAE-Sepharose and copper chelate affinity chromatography. The preparation is homogeneous by SDS-PAGE, by analytical gel filtration chromatography and by isoelectric focusing. |
| References | [1] Younus H. "Therapeutic potentials of superoxide dismutase" Int J Health Sci (Qassim)12(2018). [2] Batinic-Haberle, Ines, et al. "Rational Design of Superoxide Dismutase (SOD) Mimics: The Evaluation of the Therapeutic Potential of New Cationic Mn Porphyrins with Linear and Cyclic Substituents." Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics(2014). |
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