Tris Hydrochloride, Tris HCl, Trometamol Hydrochloride CAS 1185-53-1

• Customization: Available
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• CAS No.: 1185-53-1
• Formula: C4h12clno3
• Einecs: 214-684-5
• Samples: Available
• Purity: 99%
• Certificates: ISO9001/SGS
• Package: 1kg/5kg/10kg/25kg
• Stocks: in Stock
• Lead Time: 5-7 Working Days
• Shelf Life: 2-3 Years
• Site Audit: Available
• Transport: Air/Express/Sea
• MOQ: 10g
• Transport Package: Drum/Bottle/Bags
• Trademark: Yunbang
• Origin: China
• HS Code: 2922199090

Product Description

TRIS hydrochloride,TRIS HCL,Trometamol hydrochloride CAS 1185-53-1

TRIS hydrochloride Chemical Properties

Melting point	150-152 °C
density	1.05 g/mL at 20 °C
storage temp.	room temp
solubility	H2O: 4 M at 20 °C, clear, colorless
form	crystalline
color	clear colorless (40 % (w/w) in H2O) solution
PH	2.5-4.0 (25ºC, 4M in H2O)
PH Range	7.0 - 9.0
pka	8.1(at 25ºC)
Water Solubility	SOLUBLE
λmax	λ: 260 nm Amax: 0.12 λ: 280 nm Amax: 0.08
Sensitive	Hygroscopic
BRN	3675235
Stability:	Stable. Incompatible with strong oxidizing agents, bases, moisture.
InChIKey	QKNYBSVHEMOAJP-UHFFFAOYSA-N
CAS DataBase Reference	1185-53-1(CAS DataBase Reference)
EPA Substance Registry System	1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1185-53-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	TY2900000
F	3
TSCA	Yes
HS Code	29221980

Provider	Language
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride	English
SigmaAldrich	English
ACROS	English
ALFA	English

TRIS hydrochloride Usage And Synthesis

Chemical Properties	White crystalline powder
Uses	For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode;For Tris buffers, pH increases about 0.03 unit/°C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
Biological Activity	Commonly used laboratory reagent
Purification Methods	Crystallise the salt from 50% EtOH, then from 70% EtOH. TRIS-hydrochloride is also available commercially in a highly pure state. Otherwise, recrystallise it from 50% EtOH, then 70% EtOH, and dry it below 40o to avoid risk of decomposition. [Beilstein 4 H 304.]

TRIS hydrochloride Preparation Products And Raw materials

Preparation Products

Glycine hydrochloride-->2,2-DIMETHYL-1,3-DIOXAN-5-ONE

 

Company Informations:

Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.