| Customization: | Available |
|---|---|
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | Fluorexon |
| Synonyms: | BIS[N,N-BIS(CARBOXYMETHYL)AMINOMETHYL]FLUORESCEIN;CALCEIN;CALCEINE;CALCEIN, INDICATOR;FLUORESCEIN-2,7-BIS-METHYLIMINODIACETIC SODIUM SALT;FLUORESCEIN COMPLEXON;FLUORESCEIN COMPLEXONE;FLUORESCEIN-METHYLENE-IMINODIACETIC ACID |
| CAS: | 1461-15-0 |
| MF: | C30H26N2O13 |
| MW: | 622.53 |
| EINECS: | 215-957-1 |
| Product Categories: | Analytical Chemistry;Chelating Reagents;Complexones;Photometric Reagents (Complexone);Fluorescent;Xanthene |
| Mol File: | 1461-15-0.mol |
| Melting point | 200 °C |
| Boiling point | 662.7°C (rough estimate) |
| density | 1.4388 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: soluble |
| form | Powder |
| pka | 6.67(at 25ºC) |
| color | Yellow-orange to orange-brown |
| PH Range | Weak green ' uorescence (6.0) to strong green ' uorescence (7.2) |
| Water Solubility | insoluble |
| λmax | 494nm |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Major Application | Chemical-mechanical polishing, stabilizing liposomes, cell motility assay, detecting nucleic acids, virus, screening safety of gastric mucosa, MDR inhibitors, delivery, imaging atherosclerotic plaque |
| CAS DataBase Reference | 1461-15-0(CAS DataBase Reference) |
| EPA Substance Registry System | Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)- (1461-15-0) |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-36/37/39-26 |
| WGK Germany | 3 |
| F | 10 |
| HS Code | 32041900 |
| Chemical Properties | orange crystals |
| Uses | Calcein is used for determination of Ca in biological systems. Indicator for the fluorimetric determination of calcium in presence of Mg by complexometric titration. |
| Definition | ChEBI: Calcein is a xanthene dye. It has a role as a fluorochrome. It is functionally related to a fluoran. |
| Biological Activity | Calcein is a fluorescent dye and self-extinguishing probe that can be used as an indicator of lipid vesicle leakage, as well as a complex indicator for EDTA calcium titration and fluorescence determination of calcium. |
| Purification Methods | Dissolve it in distilled H2O and acidify with dilute HCl to pH 3.5. Filter off the solid acid and wash it well with H2O. Redissolve ca 10g in 300mL H2O containing 12g of NaOAc. Precipitate it again by adding HCl, filtering and washing with H2O. Add the solid to 200mL of EtOH stir for 1hour and filter. Repeat the EtOH wash and dry the bright yellow solid in a vacuum. This acid decomposes on heating at ca 180o. See below for the preparation of the Na salt. [Diehl & Ellingboe Anal Chem 28 882 1956]. Altenatively dissolve it in H2O and acidify with 3N HCl to pH 3.5. Collect the solid and wash it with H2O. The air-dried precipitate is extracted with 70% aqueous EtOH, filtered hot and cooled slowly. Fine yellow needles of the acid crystallise out; they are filtered off and dissolved in the minimum quantity of 0.01N NaOH and re-precipitated by adding N HCl to pH 3.5. It is then recrystallised from 70% aqueous EtOH (3x). The final product (acid) is dried at 80o in a vacuum for 24hours, m >300o(dec). It contains one molecule of water per molecule of acid (C30H36N4O13.H2O). The product is pure as revealed by electrophoresis at pH 5.6 and 8.6, and by TLC in i-BuOH/i-PrOH/AcOH/H2O (60:60:5:5 by volume) or i-PrOH or pH 8.0 borate buffer. [Wallach et al. Anal Chem 31 456 1959.] The Na salt is prepared by dissolving the pure acid in H2O containing 2 mols of NaOH per mol of acid reagent and lyophilising. It complexes with Ca and Mg ions. [Beilstein 19 III/IV 4338.] |
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