N-[2-Hydroxy-1, 1-Bis (hydroxymethyl) Ethyl]-Glycin; Tricine; Tris-HCl Buffer; Triclne; CAS 5704-04-1

• Customization: Available
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• CAS No.: 5704-04-1
• Formula: C6h13no5
• Einecs: 227-193-6
• Samples: Available
• Purity: 99%
• Certificates: ISO9001/SGS
• Package: 1kg/5kg/10kg/25kg
• Stocks: in Stock
• Lead Time: 5-7 Working Days
• Shelf Life: 2-3 Years
• Site Audit: Available
• Transport: Air/Express/Sea
• MOQ: 10g
• Transport Package: Drum/Bottle/Bags
• Trademark: Yunbang
• Origin: China
• HS Code: 2922199090

Product Description

n-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-glycin;Tricine;TRIS-HCL BUFFER;TRIClNE;CAS5704-04-1

Tricine Chemical Properties

Melting point	186-188 °C (dec.)
Boiling point	311.69°C (rough estimate)
density	1.05 g/mL at 20 °C
refractive index	1.4240 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	H2O: 4 M at 20 °C, clear, colorless
form	crystalline
color	clear colorless (40 % (w/w) in H2O) solution
Odor	Odorless
PH	4.0-6.0 (1M in H2O)
PH Range	7.4 - 8.8
pka	8.1(at 25ºC)
Water Solubility	soluble
Merck	14,9651
BRN	1937804
Stability:	Stable.
CAS DataBase Reference	5704-04-1(CAS DataBase Reference)
EPA Substance Registry System	Glycine, N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]- (5704-04-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-36/37/39
WGK Germany	3
F	3
TSCA	Yes
HS Code	29052900

MSDS Information

 

Tricine Usage And Synthesis

Descriptioin	Tricine is a zwitterionic amino acid. It is a white crystalline powder. It was first prepared by Good to buffer chloroplast reaction.1 Tricine is a commonly used electrophoresis buffer and is also used in resuspension of cell pellets^.1,2 Attributing to its higher negative charge than glycine, it can migrate faster. At the same time, its high ionic strength results in more ion movement and less protein movement. Therefore, it works as a buffer component for separation of low molecular weight peptides.^3
Reference	S. R. Haider, B. L. Sharp, H. J. Reid, A comparison of Tris‐glycine and Tris‐tricine buffers for the electrophoretic separation of major serum proteins, Journal of Separation Science, 2011, vol. 34, pp. 2463-2467 H. Schägger, G. von Jagow, Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa, Analytical Biochemistry, 1987, vol. 166, pp. 368-379
Chemical Properties	White/clear crystalline powder
Uses	Biological buffer.
Purification Methods	Crystallise Tricine from EtOH and water. [Good et al. Methods Enzymol 24B 53 1968, McGothlin & Jordan Analyt Lett 9 245 1976, Beilstein 18 III/IV 3454.]

Company Informations:

Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.