Customization: | Available |
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CAS No.: | 1637-39-4 |
Formula: | C10h13n5o |
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trans-Zeatin Chemical Properties |
Melting point | 207 °C |
Boiling point | 395.0±52.0 °C(Predicted) |
density | 1.40±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | H2O: soluble |
pka | 14.77±0.10(Predicted) |
form | powder |
color | off-white to yellow |
Merck | 14,10117 |
BRN | 616241 |
CAS DataBase Reference | 1637-39-4(CAS DataBase Reference) |
EPA Substance Registry System | Zeatin (1637-39-4) |
Safety Information |
Hazard Codes | Xi |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
RTECS | EM9506000 |
F | 8-10-23 |
HS Code | 29335990 |
Hazardous Substances Data | 1637-39-4(Hazardous Substances Data) |
trans-Zeatin Usage And Synthesis |
Chemical Properties | white to light yellow crystal powder |
Uses | Labelled Zeatin. It is purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form -induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Trans-Zeatin is a potential agent for the management of skin photoaging. |
Uses | Zeatin, purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Trans-Zeatin is a potential agent for the management of skin photoaging. |
Definition | ChEBI: The trans-isomer of zeatin. |
Purification Methods | Purify zeatin by recrystallisation from EtOH or H2O. The UV has max at 207 and 275nm ( 1,400 and 14,650) in 0.1N aqueous HCl; 212 and 270nm ( 17,050 and 16,150) in aqueous buffer pH 7.2; 220 and 276nm ( 15,900 and 14,650) in 0.1N aqueous NaOH. The picrate has m 192-194o (from H2O) from which zeatin can be recovered by treatment with Dowex-1 x 8 (200-400 mesh, OH-form). [Letham et al. Aust J Chem 22 205 1969, Proc Chem Soc (London) 230 1964, Shaw & Wilson Proc Chem Soc (London) 231 1964.] It is a cell division factor (plant growth regulator) [Letham & Palni Ann Rev Plant Physiol 34 163 1983] and inhibits mitochondrial function [Miller Plant Physiol 69 1274 1982]. The commercially available trans -9-riboside derivative, [6025-53-2], M 351.4,is a cytokine which separates from aqueous AcOH with m 177-179o. It solubility in AcOH is ~5%. [McDonald & Morris Methods Enzymol 100 347 1985]. |