CAS No 8049-47-6 Pancreatin Powder

• Customization: Available
• CAS No.: 8049-47-6
• Formula: /
• Model NO.: YB125
• EINECS: 232-468-9
• Environmental Protection: No
• Certification: ISO9001
• Color: Beige
• Classification: Coenzyme
• Function: Catalysis
• Appearance: Powder
• Type: Pharmaceutical Intermediates
• Quality: Refined
• Colour: Beige
• Samples: Available
• Certificates: ISO9001/SGS
• Package: 1kg/5kg/10kg/25kg
• Stocks: in Stock
• Lead Time: 5-7 Working Days
• Shelf Life: 2-3 Years
• Site Audit: Available
• Transport: Air/Express/Sea
• MOQ: 1 Unit
• Payment Method: LC/Tt/DAP/OA
• Form: Powder
• Purity: 99%
• Transport Package: Drum/Bottle/Bags
• Specification: 99%
• Trademark: Yunbang OEM
• Origin: China

Product Description

CAS NO 8049-47-6 Pancreatin powder

 

Company Informations

Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.

The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.
 

Product Description

Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It contains amylases, and lipases. Pancreatin is used as a digestive aid to supplement the body's own digestive enzymes, particularly in individuals with pancreatic insufficiency or those who have difficulty digesting food properly. It is commonly used to improve the digestion of fats, proteins, and carbohydrates in individuals with conditions such as cystic fibrosis, pancreatitis, or after surgical removal of the pancreas. Pancreatin is available in the form of capsules or tablets and is often taken with meals to aid in the digestion of food.

Application

Pancreatin from porcine pancreas is suitable:

• in a study to assess the treatment of steatorrhea by lipase supplementation therapy
• in a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis
• to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity.
• to assess cleavage by digestive enzymes. It is used for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors
• along with amyloglucosidase for the in vitro digestion of starch in food samples

Biochem/physiol Actions

Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
 

FAQ

1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?
A: We can have a discussion.

3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.

4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.

5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Our Advantages

1. 90days quality guarantee for exchange.

2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.

3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
 

Product analysis

Product Name:	Pancreatin
Synonyms:	beefviokase;diastasevera;ilozyme;intrazyme;PANCREATIN;PANCREATIN, 3X;PANCREATIN 4X NF;PANCREATIN 4X USP GRANULAR
CAS:	8049-47-6
MF:	N/A
MW:	0
EINECS:	232-468-9
Product Categories:	Inhibitors;Enzyme;BPC
Mol File:	Mol File

density	1.4-1.52
vapor pressure	0Pa at 25ºC
storage temp.	-20°C
solubility	Soluble or partly soluble in water forming a slightly turbid solution; practically insoluble in ethanol (96%) and in ether .
form	powder
color	beige
Water Solubility	Soluble in water. Insoluble in alcohol and ether.
Merck	13,7075
Stability:	Stable. Incompatible with alcohols, strong acids.
LogP	-1.3 at 20ºC and pH5.7-5.8
EPA Substance Registry System	Pancreatin (8049-47-6)

Hazard Codes	Xn
Risk Statements	36/37/38-42-42/43
Safety Statements	22-24-26-36/37-37/39
WGK Germany	1
RTECS	RT9033000
F	3-10
TSCA	Yes
HS Code	35079090
Hazardous Substances Data	8049-47-6(Hazardous Substances Data)
Toxicity	LD50 orl-rat: >10 g/kg YACHDS 3,2427,75

 

Chemical Properties	cream powder
Chemical Properties	Pancreatin is a yellowish to cream-colored, amorphous powder with a strong odor. Slightly soluble in water. Hazard Identification (based on NFPA-704 M Rating System): Health 1, Flammability 1, Reactivity 0. Sparingly soluble in water.
Uses	Enzyme (digestant adjunct).
Uses	Hydrolyzes starch into dextrins and sugar Pancreatin from porcine pancreas is used in the treatment of steatorrhea by lipase supplementation therapy and for pancreatic diabetes. It is also used in the removal of formalin-fixed tissues from arterial grafts without causing damage in fiber integrity. Further, it finds uses in contact lenses. In addition to this, it hydrolyzes starch into dextrins and sugar. It is also used to treat conditions responsible for deficiency in pancreatic secretions, such as surgical pancreatectomy, pancreatitis and cystic fibrosis.
Uses	Pancreatin from porcine pancreas has been used: for a study to assess the treatment of steatorrhea by lipase supplementation therapy for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity to assess cleavage by digestive enzymes. for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors. along with amyloglucosidase for the in vitro digestion of starch in food samples.
Brand name	Panteric (Parke-Davis).
Biological Functions	Pancreatin is a supplement that can result in decreased food intake. It is used for digestion, and absorption of food. Your pancreas secretes about one and one half quarts of pancreatic juice daily into the small intestine.
General Description	Pancreatin (Panteric) is a substance obtained from the fresh pancreas of the hog or the ox and contains a mixture of enzymes, principally pancreatic amylase (amylopsin), protease, and pancreatic lipase (steapsin). It converts not less than 25 times its weight of USP Potato Starch Reference Standard into soluble carbohydrates and not less than 25 times its weight of casein into proteoses. It acts best in neutral or faintly alkaline media, and excessive acid or alkali renders it inert. Pancreatin can be prepared by extracting the fresh gland with 25% alcohol or with water and subsequently precipitating with alcohol. Besides the enzymes mentioned, it contains some trypsinogen, which can be activated by intestinal enterokinase; chymotrypsinogen, which is converted by trypsin to chymotrypsin; and carboxypeptidase. Pancreatin is used largely for predigestion of food and for the preparation of hydrolysates. The value of its enzymes orally must be very small because they are digested by pepsin and acid in the stomach, although some of them may escape into the intestines without change. Even if they are protected by enteric coatings, it is doubtful they could be of great assistance in digestion.
Biochem/physiol Actions	Due to the enzymatic components such as trypsin, amylase and lipase, pancreatin hydrolyzes proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40?°C, will digest not less than 25 times its weight of casein in 60 minutes at pH7.5 at 40?°C and will release not less than 2 microequivalents of acid per min per mg pancreatin from olive oil at pH9.0 at 37?°C.
Safety Profile	Moderately toxic by subcutaneous and intraperitoneal routes.
Potential Exposure	It is an enzyme found in the pancreas and is used in medicines and in treating leather and textiles.
Metabolism	Pharmacokinetic data are not available as the enzymes act locally in the gastrointestinal tract. After exerting their action, the enzymes are digested themselves in the intestine.

 

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