Customization: | Available |
---|---|
CAS No.: | 60-10-6 |
Formula: | C13h12n4s |
Still deciding? Get samples of $ !
Request Sample
|
Suppliers with verified business licenses
Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
Product Name: | Dithizone |
Synonyms: | Dithizone,Diphenylthiocarbazone;DIPHENYLTHIOCARBAZONE, REAG;Dithizone ACS Diphenylthiocarbazone ACS;Dithizone (min. 98%);DITHIZONE FOR ANALYSIS (1,5-DIPHENYLT;N',2-Diphenyldiazenecarbothiohydrazide 98+%;Dithizone ACS reagent, >=85.0%;Dithizone Practical Grade |
CAS: | 60-10-6 |
MF: | C13H12N4S |
MW: | 256.33 |
EINECS: | 200-454-1 |
Product Categories: | Chelating Agents & Ligands;Intermediates & Fine Chemicals;Heterocycles;Pharmaceuticals |
Mol File: | 60-10-6.mol |
Dithizone Chemical Properties |
Melting point | 168 °C (dec.) (lit.) |
Boiling point | 376.1±25.0 °C(Predicted) |
density | 1.2578 (rough estimate) |
refractive index | 1.5700 (estimate) |
storage temp. | no restrictions. |
solubility | (Slightly), DMSO (Slightly), Me thanol (Slightly) |
form | Crystalline |
pka | pK1:4.50;pK2:15 (25°C) |
color | Black powder |
Water Solubility | Soluble in ethanol, dimethylsulfoxide, and pyri dine. Insoluble in water. |
Merck | 14,3377 |
BRN | 748838 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 60-10-6(CAS DataBase Reference) |
EPA Substance Registry System | Diazenecarbothioic acid, phenyl-, 2-phenylhydrazide (60-10-6) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 36-26 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | LQ9450000 |
TSCA | Yes |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29309090 |
Dithizone Usage And Synthesis |
Chemical Properties | dark brown or black crystals |
Uses | Dithizone is an organosulfur compound that acts as a chelating agent and forms complexes with metals such as lead and merc ury. Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes. |
Uses | Sensitive reagent for several heavy metals, Co, Cu, Pb, and Hg; especially for the estimation of minute amounts of Pb. |
Uses | Dithizone is used as an indicator for minute amounts of lead. It acts as a chelating agent for heavy metal poisoning. As a ligand, it forms complexes with metals like zinc, lead and mer cury. Further, it is used to assess the purity of human pancreatic islet preparations, which is used for transplantation in patients with type 1 diabetes. In addition to this, it is used as a titrant in the quantitative determination of heavy metals. |
Definition | ChEBI: Dithizone is a member of phenylhydrazines. |
General Description | Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals. |
Purification Methods | The crude dithizone is dissolved in CCl4 to give a concentrated solution. This is filtered through a sintered glass funnel and shaken with 0.8M aqueous am monia to extract dithizonate ion. The aqueous layer is washed with several portions of CCl4 to remove undesirable materials. The aqueous layer is acidified with dilute H2SO4 to precipitate pure dithizone. This is dried in a vacuum. When only small amounts of dithizone are required, purification by paper chromatography is convenient. [Cooper & Hibbits J Am Chem Soc 75 5084 1933.] Instead of CCl4, CHCl3 can be used, and the final extract, after washing with water, can be evaporated in air at 40-50o and dried in a desiccator. It complexes with Cd, Hg, Ni and Zn. [Beilstein 16 H 26, 16 IV 18.] |