| Customization: | Available |
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| CAS No.: | 9001-48-3 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Glutathione reductase is an enzyme that plays a key role in cellular antioxidant defense mechanisms by maintaining the reduced form of glutathione (GSH), a crucial cellular antioxidant. This enzyme catalyzes the reduction of oxidized glutathione (GSSG) to its reduced form (GSH) using the cofactor NADPH, contributing to the maintenance of the cellular redox balance and protection against oxidative stress.
In the presence of oxidative stress, glutathione becomes oxidized to GSSG as it scavenges free radicals and reactive oxygen species. The accumulation of GSSG can disrupt the cellular redox state, leading to oxidative damage and dysfunction. Glutathione reductase plays a vital role in preventing the accumulation of GSSG by catalyzing the reduction of GSSG back to GSH, thereby restoring the antioxidant capacity of the cell.
The activity of glutathione reductase is particularly important in tissues that are exposed to high levels of oxidative stress, such as the liver and erythrocytes. In the liver, it contributes to detoxification processes and the protection of liver cells from oxidative damage. In erythrocytes, glutathione reductase helps to maintain the redox state necessary for the proper function and stability of these cells.
Furthermore, glutathione reductase is involved in the regulation of cellular proliferation, apoptosis, and immune responses, highlighting its broader impact on cellular physiology and health.
Overall, glutathione reductase is a critical enzyme in the cellular antioxidant defense system, responsible for maintaining the redox balance by recycling oxidized glutathione back to its reduced form. Its activity is essential for protecting cells from oxidative damage and maintaining overall cellular health and function.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | EC 1.6.4.2 |
| Synonyms: | NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE;NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE II;NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE VI;GR TYPE II;GR TYPE VI;GR;NADP-dependent glutathione reductase;NADPH-glutathione reductase |
| CAS: | 9001-48-3 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 232-608-9 |
| Product Categories: | enzyme |
| Mol File: | Mol File |
| storage temp. | 2-8°C |
| form | suspension (aqueous) |
| color | yellow |
| EPA Substance Registry System | Reductase, glutathione (9001-48-3) |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| F | 10 |
| Uses | Human glutathione reductase has been used in:
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| General Description | Glutathione reductase (GLR1) exists in mitochondrial and cytoplasmic isoforms. It shares sequence and structural homology to thioredoxin reductase, and is a flavin-containing oxidoreductase. Its active site is composed of a redox-active disulphide, and it requires NADPH for its catalytic activity. It is a widely present enzyme and is found in plants, bacteria, yeast, mice and humans. |
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