Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".
We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.
R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.
Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.
Product Description
Protease from Streptomyces griseus is an enzyme derived from the bacterium Streptomyces griseus, belonging to the class of proteolytic enzymes. This protease is capable of hydrolyzing peptide bonds in proteins, resulting in the breakdown of larger protein molecules into smaller peptides and amino acids. It finds applications in various industries such as food, pharmaceuticals, and detergents, where it is utilized for its protein-degrading properties. In the food industry, it is often used for meat tenderization and flavor enhancement. In the pharmaceutical field, it may be utilized in the production of protein hydrolysates and for the removal of protein-based stains in the manufacturing of detergents.
Specificity
A mixture of at least three proteolytic activities including an extracellular serine protease. In general, serine protease display a wide range of substrate specificities, which are believed to be mediated by an active site composed of one Asp, one His, and a Ser residue in the molecule. This enzyme prefers to hydrolyze peptide bonds on the carboxyl side of glutamic or aspartic acid.
Application
Protease from Streptomyces griseus has been used:
- for the digestion of nucleus pulposus (NP) tissue
- in the catalysis of asymmetric one pot Mannich reaction
- for deproteinization of starch
- digestion of brain slices for the cell dissociation
Protease is an enzyme used to break down proteins by hydrolyzing peptide bonds. Protease is used to degrade proteins, to study protease inhibitors and to study thermal inactivation kinetics. Protease is used in nucleic acid isolation procedures in incubations. Protease from Streptomyces griseus has been used in crystallographic and kinetic investigations of the covalent complex formed by tetrapeptide aldehydes and serine protease.
Protease is typically used in nucleic acid isolation procedures in incubations of 0.5-3.0 hours supplemented with 0.2% sodium dodecyl sulfate and 10 mM EDTA.
The enzyme from Sigma has been used for the digestion and analysis of antithrombin-heparin complexes. It has also been used for the isolation of enzyme-resistant starch.
This enzyme is more active at a higher pH range than the known alkaline protease, showing the proteolytic activity even in 0.2N NaOH solution. This enzyme is useful for proteolysis of insoluble protein and for structure investigation of protein.
Biochem/physiol Actions
Protease catabolizes proteins by hydrolysis of peptide bonds. Protease are inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate. Protease from Streptomyces griseus is a mixture of at least three proteolytic activities including an extracellular serine protease. Serine protease display a wide range of substrate specificities, which are believed to be mediated by an active site composed of one Asp, one His, and a Ser residue in the molecule. This enzyme prefers to hydrolyze peptide bonds on the carboxyl side of glutamic or aspartic acid.
This product is a mixture of at least three caseinolytic activities and one aminopeptidase activity. The caseinolytic enzymes were named as Streptomyces griseus Protease A, Streptomyces griseus Protease B and Streptomyces griseus Trypsin. This product may be used when extensive or complete degradation of protein is required. This protease mixture is highly nonspecific and can digest casein to the extent of >70% as mono-amino acids.
Features and Benefits
- highly stable in pH range of 5.0 to 9.0, with peak activity at pH 8.8
- compatible with many DNA and RNA isolation buffers
- broad substrate specificity
FAQ
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Our Advantages
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
Product analysis
| Product Name: |
EC 3.4.24.4 |
| Synonyms: |
s.Griseusproteinase;Streptomycesgriseusprotease;Streptomycesgriseusproteinase;ACTINASE E, STREPTOMYCES GRISEUS;Protease from Streptomyces griseus,Actinase E, Pronase E;pronasef.streptomycesgriseus;Proteinase,streptomycesgriseus;Proteline |
| CAS: |
9036-06-0 |
| MF: |
NULL |
| MW: |
0 |
| EINECS: |
232-909-5 |
| Product Categories: |
enzyme |
| Mol File: |
Mol File |
| |
| storage temp. |
2-8°C |
| solubility |
H2O: 5-20 mg/mL |
| form |
powder |
| color |
slightly brown |
| Hazard Codes |
Xn |
| Risk Statements |
36/37/38-42 |
| Safety Statements |
22-24-26-36/37-24/25 |
| WGK Germany |
1 |
| RTECS |
UK9540000 |
| F |
10 |
| HS Code |
2934999090 |
| Uses |
Pronase E can be used to degrade antheraea pernyi silk fibroin films. |
| General Description |
Note: 1 KU = 1000 units. |
| Biochem/physiol Actions |
This product is a mixture of at least three caseinolytic activities and one aminopeptidase activity. The caseinolytic enzymes were named as Streptomyces griseus Protease A, Streptomyces griseus Protease B and Streptomyces griseus Trypsin. This product may be used when extensive or complete degradation of protein is required. This protease mixture is highly nonspecific and can digest casein to the extent of >70% as mono-amino acids. |
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