Company description:
Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".
We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.
R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.
Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.
Application
Azure B has been used for the staining of chromosomes.
Biochem/physiol Actions
Azure B is a cationic dye. It is part of the Romanowsky stain, which is used for the staining of blood films. It is also used for the localization of nucleic acids.
Suitability
Certified for use in Lillie′s modified Nocht′s method for paraffin sections and the NCCLS method for blood smears.
Product Name: |
Azure B |
Synonyms: |
N,N,N'-TRIMETHYLTHIONIN;3-(dimethylamino)-7-(methylamino)-phenothiazin-5-iumchloride;3-(dimethylamino)-7-(methylimino)-3h-phenothiazinehydrochloride;3-(dimethylamino)-7-(methylimino)-3h-phenothiazinhydrochloride;3-methylamino-7-dimethylaminophenzathoniumchloride;AZURE B, CERTIFIED (C.I. 52010);AZURE B, FOR MICROSCOPY;AZURE B CERTIFIED |
CAS: |
531-55-5 |
MF: |
C15H16ClN3S |
MW: |
305.82 |
EINECS: |
208-511-2 |
Product Categories: |
Phenothiazine |
Mol File: |
531-55-5.mol |
Azure B Chemical Properties |
Melting point |
205-210 °C (dec.)(lit.) |
storage temp. |
-20°C Freezer |
solubility |
H2O: soluble1mg/mL |
Colour Index |
52010 |
form |
Powder |
color |
Dark green |
Water Solubility |
Soluble |
λmax |
648-655 nm |
Merck |
14,6058 |
BRN |
3922630 |
Stability: |
Stable. Incompatible with strong oxidizing agents. |
Biological Applications |
Antimalarial; biofuel cell; medical devices; diagnosis of amyloid accumulation related diseases,diabetes,malignant melanoma; detecting oral cancer,cells,nucleic acids; treating avian influenza virus,nail infection,oral cavity infection |
InChIKey |
DNDJEIWCTMMZBX-UHFFFAOYSA-N |
CAS DataBase Reference |
531-55-5(CAS DataBase Reference) |
Safety Statements |
22-24/25 |
WGK Germany |
3 |
RTECS |
SO5550000 |
HS Code |
32129000 |
Provider |
Language |
SigmaAldrich |
English |
ACROS |
English |
ALFA |
English |
Azure B Usage And Synthesis |
Chemical Properties |
green crystalline powder |
Uses |
Used for staining reticulocytes. Azure B is used for preparing azure eosin stains for blood smears. |
Uses |
Biological stain. |
Uses |
Azure B is used for staining semi-thin sections of plant tissue. This dye is also useful in the NCCLS method for blood smears and Lillie's modified Nocht's method for paraffin sections. |
Definition |
ChEBI: An organic chloride salt having 3-(dimethylamino)-7-(methylamino)phenothiazin-5-ium as the counterion. It is used in making azure eosin stains for blood smear staining and is an active metabolite of methylene blue. |
Biochem/physiol Actions |
Azure B is a cationic dye. It is part of the Romanowsky stain, which is used for staining of blood films. It is also used for the localization of nucleic acids and lignin. |
Purification Methods |
Azure B has been twice recrystallised from H2O and dried at 100o/1hour in an oven. [Beilstein 27 III/IV 5151.] |
Azure B Preparation Products And Raw materials |
Raw materials |
N,N-Dimethyl-1,4-phenylenediamine |
Preparation Products |
AZURE A, CERTIFIED, PURE |