| Customization: | Available |
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| CAS No.: | 9001-03-0 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Carbonic anhydrase is an enzyme that facilitates the reversible hydration of carbon dioxide (CO2) to form bicarbonate (HCO3-) and protons (H+). This enzymatic reaction is essential for the regulation of pH balance, the transport of carbon dioxide in the blood, and the maintenance of electrolyte balance in various tissues and organs.
There are several isoforms of carbonic anhydrase, each with specific localization and functions within the body. For example, carbonic anhydrase II is found in red blood cells and plays a critical role in catalyzing the rapid conversion of carbon dioxide to bicarbonate and protons, facilitating the transport of carbon dioxide from peripheral tissues to the lungs for elimination.
In addition to its role in gas exchange and pH regulation, carbonic anhydrase is involved in various physiological processes, including electrolyte and fluid secretion in the kidneys, the secretion of gastric acid in the stomach, and the production of cerebrospinal fluid in the brain.
Furthermore, carbonic anhydrase has been targeted in the development of pharmaceutical agents for the management of conditions such as glaucoma, where inhibitors of carbonic anhydrase are used to reduce intraocular pressure.
In summary, carbonic anhydrase is an essential enzyme that catalyzes the reversible hydration of carbon dioxide, playing a crucial role in pH regulation, gas exchange, and the maintenance of electrolyte balance in various physiological processes and tissues. Its activity is fundamental for the proper functioning of multiple organ systems and the overall homeostasis of the body.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | EC 4.2.1.1 |
| Synonyms: | Dehydratase;CARBONIC ANHYDRASE FROM BOVINE ERYTHRO-CYTES, >2000 U/MG*;CARBONIC ANHYDRASE ISOZYME II, BOVINE ER YTHR., ~1800 U/MG;CARBONIC ANHYDRASE BOVINE ERYTHROCYTESAP PROX MOL W;CARBONIC ANHYDRASE, BOVINE ERYTHROCYTES FOR GEL FIL;CARBONIC ANHYDRASE FROM BOVINEERYTHROCYT ES FOR SDS;PANCREAS, BOVINE;Dehydratase, carbonate |
| CAS: | 9001-03-0 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 232-576-6 |
| Product Categories: | |
| Mol File: | Mol File |
| RTECS | MT6446000 |
| storage temp. | -20°C |
| solubility | deionized water: soluble, clear to slightly hazy, colorless (Dissolve vial contents in 0.25mL of deionised water.) |
| form | powder |
| color | white |
| Water Solubility | Soluble in water |
| Merck | 13,1822 |
| Concentration | 0.01 mCi/ml |
| Specific Activity | 3-30 μCi/mg |
| Solvent | 0.01M NaH2PO4 (pH 7.2) |
| Hazard Codes | B,Xi,T |
| Risk Statements | 36-41-40-37/38-24-20/22 |
| Safety Statements | 26-45-36/37/39-53 |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 35079090 |
| Uses | Gel filtration molecular weight marker |
| Uses | Carbonic anhydrase from human erythrocytes (HCA) has been used to study the molten-globule state of carbonic anhydrase (CA). Chaperone-like α-crystallin binds to this state of the enzyme and prevents its aggregation. The enzyme from sigma has been used for the analysis of thermodynamic stability of the enzyme. Furthermore, its clinical significance has been evaluated in human non-small cell lung cancer. |
| Uses | Carbonic anhydrase, from bovine erythrocytes, is used to create carbon dioxide capture systems and to research various purification techniques . Carbonic anhydrase is also used to study acid-base regulation in fish and carbonic anhydrase type II deficiency syndrome . |
| General Description | Carbonic Anhydrase is a metalloenzyme?with zinc. The active site of carbonic anhydrase contains three conserved histidine residues (His94, His96 and His119). |
| Biochem/physiol Actions | Carbonic anhydrase is essential for the reversible hydration of carbon dioxide. It is also crucial for the physiological processes including respiration, ion transport, acid-base balance, lipid and carbohydrate metabolic pathways. Carbonic anhydrase participates in electrolyte secretion and in the carbon dioxide fixation. |
| Purification Methods | Purify carbonic anhydrase by hydroxylapatite and DEAE-cellulose chromatography [Tiselius et al. Arch Biochem Biophys 65 132 1956, Biochim Biophys Acta 39 218 1960], and is then dialysed for crystallisation. A 0.5 to 1% solution of the enzyme in 0.05 M Tris-HCl pH 8.5 is dialysed against 1.75M solution of (NH4)2SO4 in the same buffer, and this solution is slowly increased in salt concentration by periodic removal of small amounts of dialysate and replacing with an equal volume of 3.5M (NH4)2SO4. The final salt concentration, in which the DEAE-cellulose fractions give beautiful birefringent suspensions of crystals, ranged from 2.4 to 2.7M and appeared first as fine crystals, then underwent transition to thin fragile plates. Carbonic anhydrase is a Zn enzyme which exists as several isoenzymes of varying degrees of activity [J Biol Chem 243 6474 1968, crystal structure: Nature, New Biology 235 131 1972; see also P.D. Boyer Ed. The Enzymes Academic Press NY, pp 587-665 1971]. |
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