| Customization: | Available |
|---|---|
| CAS No.: | 108-19-0 |
| Formula: | C2h5n3o2 |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
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6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | Biuret |
| Synonyms: | (aminocarbonyl)-ure;Allophamicacidamide;Allophanimidic acid;allophanimidicacid;Dicarbamylamine;Dicarbonimidic diamide;Isobiuret;L-101 |
| CAS: | 108-19-0 |
| MF: | C2H5N3O2 |
| MW: | 103.08 |
| EINECS: | 203-559-0 |
| Product Categories: | Building Blocks;Carbonyl Compounds;General Protein Quantitation;Chemical Synthesis;Organic Building Blocks;Ureas;Protein Quantitation;Quantitation Kits and Reagents |
| Mol File: | 108-19-0.mol |
| Biuret Chemical Properties |
| Melting point | 185-190 °C (dec.) (lit.) |
| Boiling point | 100 °C |
| density | 1.01 g/mL at 20 °C |
| refractive index | 1.4264 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), (Slightly, Heated, Sonicated) |
| pka | 10.17±0.46(Predicted) |
| form | Liquid |
| color | White |
| Odor | Odorless |
| Water Solubility | 2 g/100 mL (25 ºC) |
| Sensitive | Hygroscopic |
| Merck | 14,1309 |
| BRN | 1703510 |
| Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. Hygroscopic. |
| CAS DataBase Reference | 108-19-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Imidodicarbonic diamide(108-19-0) |
| EPA Substance Registry System | Imidodicarbonic diamide (108-19-0) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37-36 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29241990 |
| Hazardous Substances Data | 108-19-0(Hazardous Substances Data) |
| Biuret Usage And Synthesis |
| Outline | Biuret is the resulting product in urea production process by deamination and condensation reaction when the temperature is higher than the melting point of urea (150-170 ºC). Formula is NH2CONHCONH2. Reaction is as follows NH2CONH2-(heating)-> HNCO + NH3, HNCO + NH2CONH2 → NH2CONHCONH2, crystallization of urea in the granulation process will generate biuret, this substance is toxic to plants, thus content of biuret in urea is required not exceed 1%. Top dressing with urea, the content of biuret should not exceed 0.5%. |
| Chemical Properties | It is long white sheet crystals. Melting point is 190 ºC (decomposition), the relative density is 1.467 (-5/4 ºC). Crystals in water contain 4 molecules of water of crystallization, dehydrate at about 110 ºC. It is easily soluble in alcohol, very slightly soluble in ether. |
| Uses | 1. Biuret is used in feed for ruminants, as feed additives as urea, like, but more safe than urea. 2. It is used as pharmaceutical intermediates, foaming agents, paints. 3. It is used for chemical analysis. |
| Reaction of binary biuret | Protein produces purple in alkaline copper sulfate solution, this is because the basic copper sulfate with proteins peptide bond (-NHCO-) formed sake complexes. On the structure of purple product, generally disagree, Xu Fu (Schiff) once separated following the reaction of compound (purple crystal) from the most simple binary biuret reaction mixture, the chemical reaction equation related is as follows: Someone studied with a spectrophotometric method, suggesting that the reaction of binary biuret produces a colored substance, which is mainly composed of a tripeptide and tetrapeptide, complexes produced by ligand of copper and tripeptide was purple, complexes produced by ligand of copper with tetrapeptide was red. This reaction is not very sensitive, because its peptide bond with another substance that has other groups conduct the biuret reaction. Some substances without the peptide bonds (e.g., histidine) may also conduct this reaction, so its work on the application is limited. |
| Production method | Mix urea, water with disodium hydrogen phosphate, dissolve by heating. It was heated to 150-160 ºC, heat preservation for 2h. The reaction was completed, the reactants were poured into water and allowed to stand overnight, crystals filtered off were crude, and recrystallize with dilute am monia to give the finished product of biuret. In the production of urea, intermediate urine is as raw material, by high temperature thermal condensation, separation, and drying, the production is obtained. |
| Chemical Properties | white powder |
| Uses | Analytical reagent, especially for proteins. |
| Uses | Biuret is used in protein assay. It is also used as Catalytic agent, Petrochemical additive. It is used in organic synthesis. Biuret (Carbamoylurea) was used as a source of dietary nitrogen in purified diets for steers. |
| Definition | A colorless crystalline organic compound made by heating UREA (carbamide). It is used in a chemical test for PROTEINS. |
| Definition | ChEBI: A member of the class of condensed ureas that is the compound formed by the condensation of two molecules of urea; the parent compound of the biuret group of compounds. Used as a non-protein nitrogen source in ruminant feed. |
| Agricultural Uses | Biuret is a compound formed from urea when the temperature during the manufacture of urea goes above 140 to 170°C. A biuret concentration of more than 2% in urea is harmful to plants as it affects the metabolism of proteins. |
| Purification Methods | Crystallise biuret from EtOH. [Beilstein 3 IV 141.] |
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