| Customization: | Available |
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| CAS No.: | 9025-64-3 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Deoxyribonuclease II, derived from bovine spleen, is an endonuclease enzyme that catalyzes the hydrolysis of phosphodiester linkages in double-stranded DNA, as well as single-stranded DNA. This enzyme is distinct from Deoxyribonuclease I and is known for its preference for DNA containing regions of high GC content.
Deoxyribonuclease II has been studied for its role in the process of DNA degradation within lysosomes, where it is involved in the degradation of exogenous DNA as well as the turnover of intracellular DNA. Additionally, it has been implicated in apoptotic DNA fragmentation, playing a role in the DNA degradation associated with programmed cell death.
The enzyme's unique properties and physiological roles have made it an intriguing subject of research in the fields of molecular biology, cell biology, and immunology. Furthermore, its potential implications in various disease processes have garnered interest in exploring its therapeutic applications.
In summary, Deoxyribonuclease II from bovine spleen is a specialized endonuclease with distinct substrate preferences and physiological roles, particularly in DNA degradation within lysosomes and apoptotic DNA fragmentation. Its study holds promise for a better understanding of cellular processes and potential therapeutic implications.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | DEOXYRIBONUCLEASE II |
| Synonyms: | DNASE II;DNASE II TYPE IV;DNASE II TYPE V;deoxyribonuclease ii from bovine spleen lyo.;deoxyribonuclease ii from porcine*spleen;IUB: 3.1.22.1;Deoxyribonuclease II froM porcine spleen(Purified);DNase II, froM Pocine Pancreas |
| CAS: | 9025-64-3 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 232-801-8 |
| Product Categories: | |
| Mol File: | Mol File |
| storage temp. | -20°C |
| form | lyophilized powder |
| EPA Substance Registry System | Nuclease, deoxyribo-, II (9025-64-3) |
| WGK Germany | 3 |
| F | 10-21 |
| TSCA | Yes |
| DEOXYRIBONUCLEASE II Usage And Synthesis |
| Uses | Deoxyribonuclease II from porcine spleen has been used in an immunohistological study of the immune system cells in paraffin-embedded tissues. Deoxyribonuclease II from porcine spleen has also been used in a study to investigate its reassociation with the lysosomal membrane. |
| Uses | Deoxyribonuclease II from bovine spleen has been used:
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| Biochem/physiol Actions | Deoxyribonuclease II, also called as acid DNAse, hydrolyzes deoxyribonucleotide linkages in native and denatured DNA yielding products with 3′-phosphates. in vitro, its optimum pH range is 4.5 - 5.0. It also acts upon p-nitrophenyl-phosphodiesters at pH 5.6 - 5.9. The molecular weight is approximately 38,000 Da. |
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