Customization: | Available |
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CAS No.: | 39450-01-6 |
Formula: | C29h27n2o12p |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Proteinase K is a broad-spectrum serine protease enzyme that is widely used in molecular biology and biochemistry. It is derived from the fungus Engyodontium album and exhibits remarkable stability and activity over a wide range of conditions, including high temperatures and in the presence of denaturing agents such as SDS (sodium dodecyl sulfate).
This enzyme is valued for its ability to efficiently hydrolyze proteins, making it a valuable tool in various laboratory procedures. Proteinase K is commonly utilized for the digestion of proteins in nucleic acid purification protocols, where it effectively degrades nucleases and other proteins, thus aiding in the isolation of pure and intact nucleic acids.
Proteinase K is also employed in the study of protein structure and function, as well as in the removal of proteins from cell or tissue samples in molecular biology and histology applications. Furthermore, its utility extends to the decontamination of laboratory equipment and the inactivation of nucleases and DNases, contributing to the prevention of cross-contamination and the preservation of sample integrity.
In summary, Proteinase K is a powerful serine protease enzyme with broad substrate specificity and exceptional stability, widely utilized in molecular biology and biochemistry for the digestion of proteins, nucleic acid purification, and various other applications due to its effectiveness under a wide range of conditions.
Application
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
Product Name: | Proteinase K |
Synonyms: | ProteinaseK,PowderAndSolutionAvailable;ProteinaseK,fromTritirachiumalbumLimber;Proteinase K from Tritirachium album ca. 8 DMC-U/mg;PROTEINASEK,LYOPHILIZEDPOWDER,BIOTECHGRADE;Proteinase K for tritirachium album serine.;Proteinase K from Tritirachium album [EC 3.4.21.64] from Tritirachium album;proteinase k for tritirachium album;Proteinase K, tritirachium album serine |
CAS: | 39450-01-6 |
MF: | C29H27N2O12P |
MW: | 626.504641 |
EINECS: | 254-457-8 |
Product Categories: | Furans ,Coumarins;enzyme;39450-01-6 |
Mol File: | 39450-01-6.mol |
Proteinase K Chemical Properties |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL, slightly hazy, brown-yellow |
form | powder |
color | white |
PH | pH7.5~12 |
Water Solubility | Miscible with water. |
InChIKey | CDWGKFQEIBBJOF-BIZWTRPUNA-N |
SMILES | N12[C@](OP(O)(OC3=CC=C([N+]([O-])=O)C=C3)=O)([C@H]([C@H](O)C)C1=O)[C@](C)(OC1=CC=CC=C1)C(OC1=CC=CC=C1)=C2C(OC)=O |&1:1,16,17,22,r| |
CAS DataBase Reference | 39450-01-6 |
Hazard Codes | Xn |
Risk Statements | 36/37/38-42 |
Safety Statements | 23-24-26-36/37-22-45 |
WGK Germany | 1 |
F | 10 |
HS Code | 35079090 |
Chemical Properties | Powder beige |
Uses | Useful for the proteolytic inactivation of nucleases during the isolation of DNA and RNA. Removes endotoxins that bind to cationic proteins such as lysozyme and ribonuclease A. Reported useful for the isolation of hepatic, yeast, and mung bean mitochondria Determination of enzyme localization on membranes Treatment of paraffin embedded tissue sections to expose antigen binding sites for antibody labeling. Digestion of proteins from brain tissue samples for prions in Transmissible Spongiform Encephalopathies (TSE) research. |
Uses | A stable and highly reactive serine protease; used for protein and nucleic acid isolation.Proteinase K is used in the purification of RNA and DNA from tissues or cell lines. It finds application in protein modification, determination of enzyme localization and inactivation of RNases/DNases during nucleic acid extraction. It is also used in mitochondria isolation and removal of endotoxins bound to cationic proteins like lysozyme and ribonuclease A. Further, it is involved in the treatment of paraffin embedded tissue sections in order to expose antigen binding sites for antibody labeling. |
General Description | Proteinase K, an extracellular endopeptidase is synthesized by the mold, Tritirachium album Limber. Proteinase K belongs to a new subfamily of the subtilisins. It is a 277 amino acid protein and is characterized with an unhydrolyzed protein chain and autolyzed polypeptide chains. |
Biochem/physiol Actions | Proteinase K catalyzes the hydrolysis of keratin. |