Customization: | Available |
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CAS No.: | 4432-31-9 |
Formula: | C6h13no4s |
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4-Morpholineethanesulfonic acid Chemical Properties |
Melting point | >300 °C(lit.) |
Boiling point | 102°C |
density | 1.208 (estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | 2-8°C |
solubility | H2O: 0.5 M at 20 °C, clear |
pka | pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011 |
form | Powder |
color | White |
PH | 2.5-4.0 (25ºC in neat) |
PH Range | 5.5 - 6.7 |
λmax | λ: 260 nm Amax: 0.01 λ: 280 nm Amax: 0.01 |
Merck | 13,5929 |
BRN | 6350956 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | SXGZJKUKBWWHRA-UHFFFAOYSA-N |
CAS DataBase Reference | 4432-31-9(CAS DataBase Reference) |
EPA Substance Registry System | 4-Morpholineethanesulfonic acid (4432-31-9) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-24/25-22 |
WGK Germany | 1 |
RTECS | QE9104530 |
HS Code | 29349990 |
MSDS Information |
Application | 4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection. |
Chemical Properties | White/clear crystalline powder |
Uses | Biological buffer. |
Purification Methods | Crystallise MES from hot EtOH containing a little water. The picrate crystallises from EtOH and has m 178.8-182o. [Malkiel & Mason J Org Chem 8 199 1943, Beilstein 27 III/IV 370.] |
4-Morpholineethanesulfonic acid Preparation Products And Raw materials |
Raw materials | Sodium sulfite-->Sodium hypochlorite-->Sulfur trioxide-->LARD-->METHYL LAURATE-->Methyl palmitate |