| Customization: | Available |
|---|---|
| CAS No.: | 154-87-0 |
| Formula: | C12h19cln4o7p2s |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Cocarboxylase chloride, also known as thiamine pyrophosphate chloride, is the chloride salt form of thiamine pyrophosphate (TPP). TPP is an active form of vitamin B1 and serves as a coenzyme in various biochemical reactions, particularly in cellular energy metabolism.
Cocarboxylase chloride is utilized for its role as a coenzyme in the decarboxylation of alpha-keto acids, an essential step in the Krebs cycle and other metabolic pathways. It participates in reactions involving the conversion of pyruvate to acetyl-CoA, as well as in the metabolism of amino acids and the synthesis of neurotransmitters.
The chloride salt form of cocarboxylase may be employed in pharmaceutical formulations and in biochemical and research applications due to its stability and solubility in aqueous solutions. It is an important component in the study of enzymatic processes, metabolic pathways, and the role of coenzymes in cellular metabolism.
Overall, cocarboxylase chloride is a crucial coenzyme involved in cellular energy metabolism and metabolic pathways, and its practical attributes make it a valuable tool for pharmaceutical and research applications.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | Cocarboxylase |
| Synonyms: | ANEURINEPYROPHOSPHORIC ACID;COCARBOXYLASE;COCARBOXYLASE CHLORIDE;Thiamine, pyrophosphoric acid ester;[2-[3-[(4-Amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethoxy-hydroxy-phosphoryl]oxyphosphonic acid chloride;Thiamine diphosphate chloride;Vitamin B1;Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride |
| CAS: | 154-87-0 |
| MF: | C12H19ClN4O7P2S |
| MW: | 460.767382 |
| EINECS: | 205-836-1 |
| Product Categories: | API;Biochemistry;Vitamins;Vitamin Ingredients |
| Mol File: | 154-87-0.mol |
| Melting point | 240~241ºC |
| storage temp. | -20°C |
| solubility | H2O: soluble50mg/mL, clear to very slightly hazy, colorless |
| form | neat |
| color | White to Off-White |
| Water Solubility | It is soluble in water. |
| BRN | 3875902 |
| Stability: | Hygroscopic |
| InChIKey | YXVCLPJQTZXJLH-UHFFFAOYSA-N |
| CAS DataBase Reference | 154-87-0(CAS DataBase Reference) |
| EPA Substance Registry System | Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride (154-87-0) |
| Safety Statements | 22-24/25 |
| RIDADR | 1759 |
| WGK Germany | 3 |
| RTECS | XI7552000 |
| F | 3-8-10 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29362200 |
| Toxicity | LD50 intramuscular in mouse: > 1gm/kg |
| Originator | Actimide,Tobishi |
| Uses | Thiamine Pyrophosphate is a thiamine (T344185) derivative produced by enzyme thiamine pyrophosphatase. Thiamine pyrophosphate is a cofactor used to catalyze various biochemical reactions. |
| Uses | Cocarboxylase is a thiamine (T344185) derivative produced by enzyme thiamine pyrophosphatase. Thiamine pyrophosphate is a cofactor used to catalyze various biochemical reactions. |
| Uses | Cocarboxylase can be used in decarboxylation mechanisms in biological systems,and to investigate radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases. |
| Definition | The active coenzyme form of vitamin B1 which functions in aldehyde transfer reactions. |
| Therapeutic Function | Coenzyme, Metabolic |
| General Description | Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby forming D-glyceraldehyde-3-phosphate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. |
| Biochem/physiol Actions | Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′. |
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