| Customization: | Available |
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| CAS No.: | 11075-17-5 |
| Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Carboxypeptidase A is an enzyme that belongs to the family of exopeptidases, which catalyze the hydrolysis of peptide bonds at the carboxy-terminal end of proteins and peptides. Specifically, carboxypeptidase A cleaves off individual amino acids from the C-terminus of peptides and proteins, resulting in the release of a free amino acid. This enzymatic activity is crucial for the digestion of proteins and the processing of peptide hormones.
Carboxypeptidase A is highly specific for cleaving aromatic or aliphatic hydrophobic amino acids from the C-terminus of peptides. Its substrate specificity contributes to its role in the final stages of protein digestion, where it acts on peptides produced by the action of other proteolytic enzymes, such as trypsin and chymotrypsin. Additionally, carboxypeptidase A is involved in the processing and inactivation of peptide hormones and neuropeptides by removing specific amino acids from their C-termini.
This enzyme is found in various tissues and organs, including the pancreas, where it contributes to the processing of proenzymes into their active forms, and the intestinal mucosa, where it aids in the final breakdown of peptides into absorbable amino acids.
The activity of carboxypeptidase A is essential for the proper digestion and assimilation of dietary proteins, as well as for the regulation of peptide hormone signaling. Its enzymatic function contributes to the maintenance of nutrient supply and the modulation of physiological processes in the body.
In summary, carboxypeptidase A is an exopeptidase enzyme that plays a vital role in the hydrolysis of peptide bonds at the C-terminus of proteins and peptides, contributing to protein digestion, peptide hormone processing, and the regulation of physiological functions. Its activity is fundamental for the breakdown of dietary proteins and the modulation of peptide signaling in various biological processes.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | CARBOXYPEPTIDASE A |
| Synonyms: | Carboxypolypeptidase, Peptidyl-L-amino-acid hydrolase from bovine pancreas;Carboxypeptidase A from bovine pancreas,Carboxypolypeptidase, Peptidyl-L-amino-acid hydrolase;Peptidyl-L-amino-acid hydrolase from bovine pancreas;Carboxypeptidase A?Agarose;E.C. 3.4.12.2;E.C. 3.4.2.1;PEPTIDYL-L-AMINO-ACID HYDROLASE;PEPTIDYL-L-AMINO-ACID HYDROLASE TYPE II-PMSF |
| CAS: | 11075-17-5 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 234-297-5 |
| Product Categories: | |
| Mol File: | Mol File |
| density | 1.00 g/mL at 20 °C |
| Fp | 4 °C |
| storage temp. | 2-8°C |
| form | suspension |
| color | white |
| CAS DataBase Reference | 11075-17-5 |
| Hazard Codes | F,Xn,B,Xi |
| Risk Statements | 11-38-42-48/20-63-65-67-36-36/37/38 |
| Safety Statements | 36/37-45-62-36-26-23-16-24-22 |
| RIDADR | UN 1294 3/PG 2 |
| WGK Germany | 2 |
| F | 10 |
| Chemical Properties | Suspension (white) |
| Uses | The enzyme from Sigma has been used as a comparison to study the specificity of Metarhizium anisopliae carboxypeptidase A (MeCPA). MeCPA had been genetically engineered to facilitate the removal of polyhistidine tags from the C-termini of recombinant proteins. It has also been used to de-tyrosinate α-tubulin, in vitro, in order to induce high affinity to ethyl-N-phenylcarbamate (EPC) sepharose. |
| Definition | An enzyme that catalyzes the cleavage of amino acids from a protein at the C-terminus of a polypeptide chain. |
| General Description | Carboxypeptidase A-agarose product is prepared by the immobilization of carboxypeptidase A, originally isolated from the bovine pancreas, to activated 4% crosslinked beaded agarose. |
| Industrial uses | Carboxypeptidase A(CPA) is an enzyme of the digestive system that is known to cleave amino acids favouring the C-terminal end as well as certain esters. This enzymatic activity depends on the metal at the catalytic site. Zn2+ and some Co2+-containing CPAs exhibit peptidase function, whilst esterase function has been seen by CPAs containing a variety of divalent d-block metals. CPA has a size similar to CA, consisting of about 300 amino acids and a molecular mass of 34 kDa. |
| Biochem/physiol Actions | Carboxypeptidase as isolated from bovine pancreas glands is a metalloenzyme that contains 1 g atom of zinc per mole of protein. It catalyzes the hydrolysis of the carboxyl-terminal peptide bond in peptides and proteins. It is primarily specific to aromatic and hydrophobic side chains such as phenylalanine, tryptophan or leucine. The enzyme also exhibits esterase activity. It is inhibited by beta-phenylpropionate and indole acetate. |
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