• CAS 39445-21-1 Elastase Powder
  • CAS 39445-21-1 Elastase Powder
  • CAS 39445-21-1 Elastase Powder
  • CAS 39445-21-1 Elastase Powder
  • CAS 39445-21-1 Elastase Powder
  • CAS 39445-21-1 Elastase Powder

CAS 39445-21-1 Elastase Powder

CAS No.: 39445-21-1
Formula: /
EINECS: 254-453-6
Environmental Protection: No
Certification: ISO9001
Color: White
Samples:
US$ 2/Bag 1 Bag(Min.Order)
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Customization:
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  • Overview
  • Company Informations
  • Product Description
  • FAQ
  • Our Advantages
  • Product analysis
  • Detailed Photos
Overview

Basic Info.

Model NO.
YB193
Classification
Coenzyme
Function
Catalysis
Appearance
Powder
Type
Pharmaceutical Intermediates
Quality
Refined
Colour
White
Samples
Available
Certificates
ISO9001/SGS
Package
1kg/5kg/10kg/25kg
Stocks
in Stock
Lead Time
5-7 Working Days
Shelf Life
2-3 Years
Site Audit
Available
Transport
Air/Express/Sea
MOQ
1 Unit
Payment Method
LC/Tt/DAP/OA
Form
Powder
Purity
99%
Transport Package
Drum/Bottle/Bags
Specification
30u/mg
Trademark
Yunbang OEM
Origin
China

Product Description

CAS 39445-21-1 Elastase powder
 
Company Informations

Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.

The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.


Our goal : To achieve the integrated upgrade of Pharmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.

 
Product Description

The main function of elastase is to hydrolyze peptide bonds in elastin, leading to the breakdown of this structural protein. By cleaving elastin, elastase contributes to tissue remodeling, repair, and the regulation of elastic properties in various physiological processes, such as wound healing, inflammation, and maintenance of tissue structure and function.

Elastase exhibits a high degree of specificity for elastin, targeting specific amino acid residues within the protein. This specificity allows elastase to selectively degrade elastin without significantly affecting other proteins in the extracellular matrix.

In addition to its role in physiological processes, elastase is also implicated in certain pathological conditions, particularly in the context of inflammatory diseases such as chronic obstructive pulmonary disease (COPD) and certain types of emphysema. In these conditions, uncontrolled elastase activity can lead to excessive degradation of lung tissue, contributing to the loss of elasticity and impaired lung function.

The activity of elastase is tightly regulated in the body to prevent excessive tissue damage. Imbalances in elastase activity can have significant implications for tissue integrity and function, making it an important target for research in both health and disease.

In summary, elastase is a serine protease enzyme that specifically targets elastin, playing a key role in the degradation and remodeling of this important structural protein in various physiological and pathological processes. Its activity is essential for tissue repair and maintenance, but dysregulation can contribute to disease states, particularly in the context of inflammatory conditions.

Application

Elastase from porcine pancreas has been used in a study to investigate the design, synthesis and evaluation of biomimetic affinity ligands for elastases. Elastase from porcine pancreas has also been used in a study to investigate the purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin, and elastase.
Elastase from porcine pancreas has been used:
  • to induce abdominal aortic aneurysm (AAA)
  • to study the impact of indoleamine 2-3 dioxygenase 1 (IDO) in mice
  • to digest aortas for aortic smooth muscle cells (SMC) isolation
  • as a positive control of proteolytic digestion
FAQ

1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?
A: We can have a discussion.

3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.

4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.

5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Our Advantages

1. 90days quality guarantee for exchange.

2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.

3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.

 

Product analysis
Product Name: Elastase
Synonyms: EC 3.4.21.36;EC 3.4.21.37;ELASTASE, LEUKOCYTE;ELASTASE, NEUTROPHIL, HUMAN;ELASTASE, HUMAN NEUTROPHIL;ELASTASE, HUMAN NEUTROPHILS;Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free;Elastase froM porcine pancreas(Lyophilized)
CAS: 39445-21-1
MF: NULL
MW: 0
EINECS: 254-453-6
Product Categories:  
Mol File: Mol File
 
RTECS  TS5052000
storage temp.  -20°C
solubility  H2O: soluble
form  lyophilized powder
color  white
Water Solubility  Soluble in water.
Hazard Codes  B,Xn
Risk Statements  36/37/38-42
Safety Statements  23-24-26-36/37-22
WGK Germany  3
3-10
 
Uses Elastase from porcine pancreas has been used in a study to identify a novel bone/calcium metabolism-regulating factor in porcine pancreas. Elastase from porcine pancreas has also been used in a study to investigate the effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs.
Uses Elastase from porcine pancreas has been used:
  • to treat vero cells?to study its effects on syncytium formation
  • as a positive control in protease assays
  • as a component in RPMI 1640 to isolate human aortic smooth muscle cells (HASMCs) from the aortic tissue
General Description Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin.
 
Detailed Photos

 

CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder
CAS 39445-21-1 Elastase Powder



 

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Diamond Member Since 2021

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Manufacturer/Factory
Registered Capital
10000000 RMB
Plant Area
>2000 square meters