Customization: | Available |
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CAS No.: | 39445-21-1 |
Formula: | / |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".The main function of elastase is to hydrolyze peptide bonds in elastin, leading to the breakdown of this structural protein. By cleaving elastin, elastase contributes to tissue remodeling, repair, and the regulation of elastic properties in various physiological processes, such as wound healing, inflammation, and maintenance of tissue structure and function.
Elastase exhibits a high degree of specificity for elastin, targeting specific amino acid residues within the protein. This specificity allows elastase to selectively degrade elastin without significantly affecting other proteins in the extracellular matrix.
In addition to its role in physiological processes, elastase is also implicated in certain pathological conditions, particularly in the context of inflammatory diseases such as chronic obstructive pulmonary disease (COPD) and certain types of emphysema. In these conditions, uncontrolled elastase activity can lead to excessive degradation of lung tissue, contributing to the loss of elasticity and impaired lung function.
The activity of elastase is tightly regulated in the body to prevent excessive tissue damage. Imbalances in elastase activity can have significant implications for tissue integrity and function, making it an important target for research in both health and disease.
In summary, elastase is a serine protease enzyme that specifically targets elastin, playing a key role in the degradation and remodeling of this important structural protein in various physiological and pathological processes. Its activity is essential for tissue repair and maintenance, but dysregulation can contribute to disease states, particularly in the context of inflammatory conditions.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
Product Name: | Elastase |
Synonyms: | EC 3.4.21.36;EC 3.4.21.37;ELASTASE, LEUKOCYTE;ELASTASE, NEUTROPHIL, HUMAN;ELASTASE, HUMAN NEUTROPHIL;ELASTASE, HUMAN NEUTROPHILS;Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free;Elastase froM porcine pancreas(Lyophilized) |
CAS: | 39445-21-1 |
MF: | NULL |
MW: | 0 |
EINECS: | 254-453-6 |
Product Categories: | |
Mol File: | Mol File |
RTECS | TS5052000 |
storage temp. | -20°C |
solubility | H2O: soluble |
form | lyophilized powder |
color | white |
Water Solubility | Soluble in water. |
Hazard Codes | B,Xn |
Risk Statements | 36/37/38-42 |
Safety Statements | 23-24-26-36/37-22 |
WGK Germany | 3 |
F | 3-10 |
Uses | Elastase from porcine pancreas has been used in a study to identify a novel bone/calcium metabolism-regulating factor in porcine pancreas. Elastase from porcine pancreas has also been used in a study to investigate the effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs. |
Uses | Elastase from porcine pancreas has been used:
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General Description | Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin. |