| Customization: | Available |
|---|---|
| CAS No.: | 85-61-0 |
| Formula: | C21h36n7o16p3s |
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Hunan Yunbang Pharmaceutical Co., Ltd. (Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".Coenzyme A, often abbreviated as CoA, is a vital coenzyme involved in numerous metabolic pathways within living organisms. It plays a crucial role in the synthesis and oxidation of fatty acids, the oxidation of pyruvate in the citric acid cycle, and the metabolism of amino acids and carbohydrates.
Coenzyme A functions as a carrier of acyl groups in cells, facilitating the transfer of these groups in metabolic reactions. Its primary function is to activate carboxylic acids, forming thioester derivatives that are essential intermediates in various metabolic processes.
Furthermore, Coenzyme A is integral to the production of acetyl-CoA, a pivotal molecule that enters the citric acid cycle to generate energy in the form of ATP. This process occurs in the mitochondria and is essential for cellular respiration and energy production.
Coenzyme A is derived from pantothenic acid, which is a component of vitamin B5. It is a fundamental coenzyme in cellular metabolism, participating in reactions that are central to energy production and the synthesis of important biomolecules.
Overall, Coenzyme A is a key player in cellular metabolism, serving as a carrier of acyl groups and playing a central role in the synthesis and breakdown of nutrients for energy production and cellular maintenance.
1:Can I get some samples before bulk order?
A: Most products provide free samples, but the shipping cost be paid by customers.
2: What's your MOQ?
A: We can have a discussion.
3: Which kind of payment terms do you accept?
A: PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union,D/P, ETC.
4.How to place an order?
A: You can contact me through Trademanager, WhatsApp, Email and other contact methods, tell me the product and quantity you need, and then we will give you a quote.
5:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
1. 90days quality guarantee for exchange.
2. For each batch order extracts, we will attach a factory Inspection Report with the goods delivery , including the BatchNo/ Date/ Test index ects; also will keep the archived extracts to ensure received by customers are the same each time.
3. Our team of experienced professionals are available online 24 hours a day to answer any questions and provide guidance on product usage and maintenance.
| Product Name: | Coenzyme A |
| Synonyms: | [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-(2-sulfanylethylcarbamoyl)ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid;CONENZYME A;Coenzyme a, free acid;Coenzyme A, free acid, lyophilized, min. 75% (enzym.);COENZYME A FREE ACID FROM YEAST;Coenzyme A, free acid, lyophilized, 75%;Coenzyme A / Q0 / Q10;COENZYM A FREE ACID |
| CAS: | 85-61-0 |
| MF: | C21H36N7O16P3S |
| MW: | 767.53 |
| EINECS: | 201-619-0 |
| Product Categories: | Vitamin series;85-61-0 |
| Mol File: | 85-61-0.mol |
| density | 1.96±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| pka | 9.6 (thiol); pK 6.4 (secondary phosphate); pK 4.0 (adenine NH3+) |
| Merck | 13,2491 |
| BRN | 77809 |
| LogP | -4.358 (est) |
| EPA Substance Registry System | Coenzyme A (85-61-0) |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| F | 1-10 |
| TSCA | Yes |
| HS Code | 2933299090 |
| Description | Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a 5-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway has been identified as a target for the development of antibacterial compounds. |
| Chemical Properties | yellowish lyophilisate |
| Uses | A hydrated form of Coenzyme A (CoA) is a useful biochemical research chemical, used in the preparation of high-yielding cell-free protein synthesis platforms. |
| Uses | Coenzyme A hydrate has been used in the thiolase enzyme assay of recombinant acetoacetyl-CoA thiolase (rACAT) in Clonorchis sinensis. It may be used as a reference standard in Raman spectra measurements. |
| Definition | ChEBI: Tetraanion of coenzyme A. |
| General Description | Coenzyme A is structurally composed of 2-aminoethanethiol, pantothenic acid and phosphorylated adenosine phosphate. |
| Biochem/physiol Actions | Coenzyme A is a cofactor involved in acyl group transfer. It is essential for carbohydrate, lipid and protein metabolism. Coenzyme A acts as a cofactor for vitamin B coenzymes. |
| Purification Methods | The white powder is best stored in an inert atmosphere in the dark in sealed ampoules after drying in vacuo over P2O5 at 34o. It has UV: max 259 nm ( 16,800) in H2O. [Buyske et al. J Am Chem Soc 76 3575 1954.] It is soluble in H2O but insoluble in EtOH, Et2O and M2CO. It is readily oxidised in air and is best kept as the more stable trilithium salt [Moffat & Khorana J Am Chem Soc 83 663 1961; see also Beinert et al. J Biol Chem 200 384 1953, De Vries et al. J Am Chem Soc 72 4838 1950, Gregory et al. J Am Chem Soc 74 854 1952 and Baddiley Adv Enzymol 16 1 1955]. [Beilstein 26 III/IV 3663.] |
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