Customization: | Available |
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CAS No.: | 372-75-8 |
Formula: | C6h13n3o3 |
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Melting point | 214 °C |
alpha | 25.5 º (c=8, 6N HCl) |
Boiling point | 306.48°C (rough estimate) |
density | 1.2919 (rough estimate) |
refractive index | 26 ° (C=8, 6mol/L HCl) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
pka | 2.43(at 25ºC) |
form | Crystals or Crystalline Powder |
color | White |
Odor | Odorless |
Water Solubility | 200 g/L (20 ºC) |
Merck | 14,2331 |
BRN | 6055157 |
InChIKey | RHGKLRLOHDJJDR-BYPYZUCNSA-N |
CAS DataBase Reference | 372-75-8(CAS DataBase Reference) |
EPA Substance Registry System | L-Ornithine, N5-(aminocarbonyl)- (372-75-8) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 24/25-36-26 |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29241900 |
L-Citrulline Usage And Synthesis |
Chemical Properties | White powder |
Originator | StaminO2,ErgoPharm |
Uses | An amino acid, L-Citrulline can be used in the treatment of asthenia and as an essential intermediate in the biosynthesis of nitric o xide. |
Uses | An essential intermediate in the biosynthesis of ni tric oxide. |
Manufacturing Process | Citrulline is obtained as a result of a reaction of L-arginine hydrochloride with sodium hydroxi de, copper oxide and hydrogen sulfide. In practice it is usually used as malate salt |
Therapeutic Function | Stimulant, Detoxicant |
Purification Methods | Likely impurities are arginine and ornithine. Crystallise S-citrulline from water by adding 5 volumes of EtOH. Also crystallise it from water by addition of MeOH. [Ellenbogen J Am Chem Soc 74 5198 1952, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2491-2494 1961, Beilstein 4 IV 2647.] |
L-Citrulline Preparation Products And Raw materials |
Raw materials | Hydroxide |
Preparation Products | H-LYS(ALLOC)-OH-->MC-Val-Cit-PAB-->FMoc-Val-Cit-PAB-->FMoc-Val-Cit-PAB-PNP-->L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]- |